Strat-M® Membrane Compound Data

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Strat-M® Membrane Can Predict Transdermal Diffusion of a Variety of Compounds.
Strat-M® membrane is predictive of diffusion of human skin for a wide variety of active compounds and formulations. Use the Compound Correlation Tool to learn how Strat-M® membrane will work for you.

Strat-M® transdermal diffusion membrane compound data
Strat-M® membrane was tested alongside two lots of human cadaver skin in a Franz diffusion cell apparatus (0.635 cm2). Three Franz cells were used for Strat-M® membrane and each lot of skin. The donor compartment of each cell was loaded with 500 µL of a saturated diclofenac solution. Data represents average cumulative flux at each test point.



Strat-M® transdermal diffusion data for acetyl salicylic acid compared to human skin
The diffusion rate of acetyl salicylic acid (Aspirin) through Strat-M® membrane was measured on a Franz diffusion cell apparatus (0.635 cm2). Six Franz cells were used. The donor compartment of each cell was loaded with 500 µL of a saturated acetyl salicylic acid solution. Diffusion performance was compared to published values for 8-hour cumulative diffusion rate through human cadaver and porcine skin. Data represents average cumulative flux at each test point.



Strat-M® transdermal diffusion data for octocrylene compared to human skin
Strat-M® membrane was tested alongside human cadaver skin in a Franz diffusion cell apparatus (0.635 cm2). Three Franz cells were used for each test model. The donor compartment of each cell was loaded with 500 μL of a Octocrylene emulsion (3.5%). Data represents average cumulative flux at each test point.

Note: Information presented is based on preliminary development tests. Official claims will be based on product validation results.