C110395Millipore’s AMPK Antibodies demonstrate specificity against AMP-activated protein kinase, which regulates metabolism. See below related products, based on the expertise of Upstate & Chemicon.
AMPK Antibodies, Kits & Proteins
AMP-activated protein kinase (AMPK) is a metabolic and stress-sensing kinase that is a target for treating Type 2 diabetes and obesity. The Alpha subunit has isoforms, alpha 1 and alpha 2. AMPK is phosphorylated by upstream kinases, AMPK Kinase (AMPKK) and LKB1 which results in its activation. Active AMPK regulates metabolism by phosphorylating rate-limiting enzymes in metabolic pathways and controlling gene expression.