CBL168F | Anti-CD36 Antibody, clone SM-phi, FITC conjugated

CBL168F
100 assays  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IHCMFITCMonoclonal Antibody
      Description
      Catalogue NumberCBL168F
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-CD36 Antibody, clone SM-phi, FITC conjugated
      Alternate Names
      • Platelet Glycoprotein IV
      References
      Product Information
      FormatFITC
      PresentationThe monoclonal was purified by affinity chromatography and gel filtration prior to conjugation. The conjugate is supplied in 1.0 ml of phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
      Applications
      ApplicationThis Anti-CD36 Antibody, clone SM-phi, FITC conjugated is validated for use in FC, IH for the detection of CD36d. This antibody has been tested in Human.
      Key Applications
      • Flow Cytometry
      • Immunohistochemistry
      Application NotesStudies of platelet and monocyte receptor for thrombospondin

      Studies of platelet collagen adhesion receptor

      Flow cytometry

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenHuman tonsil cells and peripheral blood mononuclear cells
      CloneSM-phi
      HostMouse
      SpecificityThis antibody recognizes the 90 kDa single chain membrane glycoprotein (GPIIIb) that is found on monocytes/macrophages and platelets. FUSION PARTNER: NS1 myeloma cell line
      IsotypeIgM
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
      Gene Symbol
      • CD36
      • PAS-4
      • GPIV
      • FAT
      • CHDS7
      • GP3B
      • SCARB3
      • PASIV
      • GP4
      • GPIIIB
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16671 # Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
      SIZE: 472 amino acids; 53053 Da
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      PTM: N-glycosylated and O-glycosylated with a ratio of 2:1.
      DISEASE: SwissProt: P16671 # Defects in CD36 are the cause of platelet glycoprotein IV deficiency [MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. & Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].
      SIMILARITY: SwissProt: P16671 ## Belongs to the CD36 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C for up to one year.
      Packaging Information
      Material Size100 assays
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HUMAN CD36 FITC 2424780
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2398913 2398913
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2045564 2045564
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2193302 2193302
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2207165 2207165
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY -2639924 2639924
      MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY -2730856 2730856

      References

      Reference overviewPub Med ID
      Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine.
      Greenwalt, D E, et al.
      Blood, 80: 1105-15 (1992)  1992

      1381234 1381234

      Data Sheet

      Title
      Anti-CD36, FITC Conjugated, Clone SM-phi, FITC Conjugated - Data Sheet

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      Alternative Format

      Catalogue Number Description  
      CBL168 Anti-CD36 Antibody, clone SM-phi Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies