Key Spec Table
|Species Reactivity||Key Applications||Host||Format||Antibody Type|
|H, M, Rb||FC||M||Phycoerythrin||Monoclonal Antibody|
|Description||Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated|
|Safety Information according to GHS|
|Storage and Shipping Information|
|Storage Conditions||Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.|
|Material Size||100 assays|
|Reference overview||Pub Med ID|
|cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.|
Lanza, F, et al.
J. Biol. Chem., 266: 10638-45 (1991) 1991
This study was designed to clone, sequence, and express the full-length cDNA for the human platelet p24/CD9 antigen. A 1.3-kilobase cDNA clone was identified that has an open reading frame encoding a mature protein of 228 amino acids (approximately 25,400 Da) containing 10 cysteine residues and four putative transmembrane domains. The identity of the clone was confirmed by: (i) its predicted size, (ii) identity to four peptide sequences from the isolated protein including the NH2 terminus, and (iii) expression of the isolated clone in Xenopus oocytes and Chinese hamster ovary cells. p24/CD9 has sequence identity (24-34%) to four other cell-surface proteins: ME491, a melanoma antigen; CO-029, a carcinoma antigen; CD37, a leukocyte antigen; and SM23, an antigen of the parasitic helminth Schistosoma mansoni. The five proteins have a similar number of amino acids and are characterized by the presence of four putative transmembrane domains. These data indicate the presence of a new family of surface antigens that may function in cellular activation and differentiation.
|Stimulus-response coupling in human platelets activated by monoclonal antibodies to the CD9 antigen, a 24 kDa surface-membrane glycoprotein.|
Carroll, R C, et al.
Biochem. J., 266: 527-35 (1990) 1990
|MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY|