CBL162P | Anti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated

CBL162P
100 assays  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RbFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberCBL162P
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated
      Alternate Names
      • MRP-1
      • DRAP-27
      References
      Product Information
      FormatPhycoerythrin
      PresentationThe conjugate is supplied as a 100 test vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
      Applications
      ApplicationAnti-CD9 Antibody, clone MM2/57, Phycoerythrin conjugated is an antibody against CD9 for use in FC.
      Key Applications
      • Flow Cytometry
      Application NotesCharacterization of leukaemias and lymphomas

      Bone marrow purging in autologous bone marrow trans-plantation

      Platelet inhibition and aggregation studies and association with CD41/CD61

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenHuman platelet glycoprotein
      CloneMM2/57
      HostMouse
      SpecificityThis antibody reacts with a 25 kDa molecular weight band on gels of non-reduced platelet membranes and immunopre-cipitates a similar band from I125 labelled platelets. The antigen is expressed on eosinophils, granulocytes, monocytes and numerous stromal cells. This CD9 antigen belongs to the TM4 superfamily of cell surface proteins with the N- and C-terminals cytoplasmically located. This antibody reacts immuno-histochemically on frozen sections of platelets, monocytes and pre-B cells with differential staining on lymphoid and epithelial tissues.
      .
      KNOWN SPECIES CROSS REACTIVITY: Positive with rabbit platelets and fibroblasts and mouse
      FUSION PARTNER: NS1 myeloma cell line
      IsotypeIgG2bκ
      Species Reactivity
      • Human
      • Mouse
      • Rabbit
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance.
      Gene Symbol
      • CD9
      • Tspan-29
      • MRP-1
      • MIC3
      • p24
      • Tetraspanin-29
      • BA2
      • BTCC-1
      • 5H9
      • TSPAN29
      • GIG2
      • DRAP-27
      • P24
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P21926 # Involved in platelet activation and aggregation. Regulates paranodal junction formation. Required for gamete fusion. Involved in cell adhesion, cell motility and tumor metastasis.
      SIZE: 228 amino acids; 25416 Da
      SUBUNIT: Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.
      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: Expressed by a variety of hematopoietic and epithelial cells.
      PTM: Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids. & Phosphorylated on tyrosine following B-cell activation.
      SIMILARITY: SwissProt: P21926 ## Belongs to the tetraspanin (TM4SF) family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.
      Packaging Information
      Material Size100 assays
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY - 2359855 2359855
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED - 2536830 2536830
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED -2694540 2694540
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY - 2019774 2019774
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY - 2191957 2191957
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY -2507759 2507759

      References

      Reference overviewPub Med ID
      cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins.
      Lanza, F, et al.
      J. Biol. Chem., 266: 10638-45 (1991)  1991

      Show Abstract
      2037603 2037603
      Stimulus-response coupling in human platelets activated by monoclonal antibodies to the CD9 antigen, a 24 kDa surface-membrane glycoprotein.
      Carroll, R C, et al.
      Biochem. J., 266: 527-35 (1990)  1990

      2317202 2317202

      Data Sheet

      Title
      MOUSE ANTI-HUMAN CD9 R-PE CONJUGATED MONOCLONAL ANTIBODY

      Related Products & Applications

      Related Products

      Catalogue Number Description  
      CBL162 Anti-CD9 Antibody, clone MM2/57 Show Pricing & Availability

      Alternative Format

      Catalogue Number Description  
      CBL162 Anti-CD9 Antibody, clone MM2/57 Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies