CBL186 | Anti-DNA Antibody, clone AC-30-10

CBL186
50 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AIF, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL186
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-DNA Antibody, clone AC-30-10
      Alternate Names
      • Deoxyribonucleic acid
      References
      Product Information
      FormatPurified
      PresentationThe immunoglobulin was purified by gel filtration and presented in PBS, pH 7.4, containing 0.09% sodium azide.
      Applications
      ApplicationAnti-DNA Antibody, clone AC-30-10 is a Mouse Monoclonal Antibody for the detection of DNA & has been validated in IF, IHC(P).
      Key Applications
      • Immunofluorescence
      • Immunohistochemistry (Paraffin)
      Application NotesResearch (cell biology, molecular biology, microbiology) since it reacts with any form of native and denatured DNA. Reliable positive control in immunofluoresence assays for detecting DNA antibodies on tissues of cultured cells, notably in the diagnosis of autoantibodies and autoimmune diseases.

      Sensitive detection of mycoplasma contamination in cell cultures.
      For frozen and paraffin tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      CloneAC-30-10
      HostMouse
      SpecificityThis antibody reacts with native denatured DNA extracted from various organisms: mouse DNA, calf thymus DNA, M13 DNA, SV-40 DNA and several plasmids. It also reacts with synthetic DNA of different base compositions: poly dAT-poly dAT, poly dAT. DNA-containing structures such as chromatin in diverse tissues from several species as well as in diverse cell lines such as XLKE-A6 (Xenopus), RVF-SMC (rat kangaroo) and HeLa (human) are also recognized.
      IsotypeIgM
      Species Reactivity
      • All
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C for up to 12 months from date of receipt.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-DNA MONOCLONAL ANTIBODY - 2119994 2119994
      MOUSE ANTI-DNA MONOCLONAL ANTIBODY - 2387445 2387445
      MOUSE ANTI-DNA MONOCLONAL ANTIBODY - 2433306 2433306
      MOUSE ANTI-DNA - 2147022 2147022
      MOUSE ANTI-DNA -2578584 2578584
      MOUSE ANTI-DNA -2608475 2608475
      MOUSE ANTI-DNA -2615057 2615057
      MOUSE ANTI-DNA -2640546 2640546
      MOUSE ANTI-DNA -2670395 2670395
      MOUSE ANTI-DNA -2676801 2676801

      References

      Reference overviewPub Med ID
      Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.
      Wang, YE; Marinov, GK; Wold, BJ; Chan, DC
      PloS one  8  e74513  2013

      Show Abstract
      23991223 23991223
      High sensitivity immunolocalization of double and single-stranded DNA by a monoclonal antibody.
      Scheer, U, et al.
      Eur. J. Cell Biol., 43: 358-71 (1987)  1987

      Show Abstract
      3305019 3305019

      Data Sheet

      Title
      Anti-DNA, clone AC-30-10 - Data Sheet