CBL271 | Anti-Fibroblasts Antibody, clone TE-7

CBL271
100 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IF, IHC, ICCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL271
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Fibroblasts Antibody, clone TE-7
      References
      Product Information
      FormatPurified
      PresentationThe monoclonal is presented at a concentration of 100 μg/mL in phosphate buffered saline containing 10 mM sodium azide and 1 mg/mL bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
      Applications
      ApplicationThis Anti-Fibroblasts Antibody, clone TE is validated for use in Flow Cytometry (FC), Immunocytochemistry (ICC), Immunofluorescence (IF) and Immunohistochemistry (IHC) for the detection of Fibroblasts.
      Key Applications
      • Flow Cytometry
      • Immunofluorescence
      • Immunohistochemistry
      • Immunocytochemistry
      Application NotesImmunohistochemistry Analysis: A representative lot immunostained fibroblastic cells in paraffin-embedded gastrocnemius section from a patient with myopathic condition (Courtesy of Duy Minh Ha, University of Nebraska Medical Center, Omaha, NE)
      Immunocytochemistry Analysis: A representative lot immunostained human muscle fibroblasts by fluorescent immunocytochemistry (Agley, C.C., et al. (2015). J. Vis. Exp. (95):52049).
      Immunocytochemistry Analysis: A representative lot immunostained MRC-5 fetal fibroblasts and normal human dermal fibroblasts (NHDF), but not fibrocytes or macrophages by immunocytochemistry (Bertolotto, C., et al. (2009). PLoS One. 4(10):e7475).
      Flow Cytometry Analysis: A representative lot detected fibroblasts differentiated from human ESCs and iPSCs (Zhang, J., et al. (2012). Circ. Res. 111(9):1125-1136).
      Immunofluorescence Analysis: A representative lot immunostained fibroblasts in human skeletal muscle cryosections by fluorescent immunohistochemistry (Agley, C.C., et al. (2013). J. Cell. Sci. 126(Pt 24):5610-5625).
      Immunofluorescence Analysis: A representative lot immunostained the fibrous stroma and vessels in acetone-fixed, frozen human tissue sections by fluorescent immunohistochemistry (Haynes, B.F., et al. (1984). J. Exp. Med. 159(4):1149-1168).
      Biological Information
      ImmunogenWhole human thymic stoma cells (Haynes, B.F., et al. (1984). J. Exp. Med. 159(4):1149-1168).
      CloneTE-7
      HostMouse
      SpecificityThe antibody reacts with fibroblasts in tissue as well as cultured fibroblasts. On skin sections the antibody reacts with stratum basal epidermal cells. The antigen defined by antibody TE-7 appears to be a marker for mesodermally dervied (mesenchymal) human connective tissue and tumors derived from such tissue, e.g. fibrosarcomas (Haynes, B.F., et al. (1984). J. Exp. Med. 159(4):1149-1168). The antibody is useful for the assessment of thymic epithelial culture contamination with fibroblasts, and the identification of cells of mesodermal origin in the fetus.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsFor use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      CBL271 - 2278524 2278524
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2147068 2147068
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2325116 2325116
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2424485 2424485
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2035065 2035065
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2070827 2070827
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2561987 2561987
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY - 2564857 2564857
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY -2477002 2477002
      MOUSE ANTI-HUMAN FIBROBLASTS MONOCLONAL ANTIBODY -2506436 2506436

      References

      Reference overviewPub Med ID
      Embryonic motoneuron-skeletal muscle co-culture in a defined system.
      M Das, J W Rumsey, C A Gregory, N Bhargava, J-F Kang, P Molnar, L Riedel, X Guo, J J Hickman
      Neuroscience  146  481-8  2007

      Show Abstract
      17383103 17383103
      The human thymic microenvironment. Phenotypic characterization of Hassall's bodies with the use of monoclonal antibodies.
      Lobach, D F, et al.
      J. Immunol., 134: 250-7 (1985)  1985

      Show Abstract
      2578044 2578044
      Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic microenvironment.
      Haynes, B F, et al.
      J. Exp. Med., 159: 1149-68 (1984)  1984

      Show Abstract
      6200562 6200562
      The human thymic microenvironment.
      Haynes, B F
      Adv. Immunol., 36: 87-142 (1984)  1984

      Show Abstract
      6209968 6209968
      Intrathymic and extrathymic T cell maturation.
      Stutman, O
      Immunol. Rev., 42: 138-84 (1978)  1978

      32648 32648

      Data Sheet

      Title
      Anti-Fibroblasts, clone TE - 7 - Data Sheet