04-357 | Anti-Glycogen Synthase CT Antibody, rabbit monoclonal

04-357
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RFC, IF, IP, WB, IH(P)RbPurifiedMonoclonal Antibody
      Description
      Catalogue Number04-357
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Glycogen Synthase CT Antibody, rabbit monoclonal
      Alternate Names
      • GYS
      • GSY
      References
      Product Information
      FormatPurified
      Presentation100 μL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90 mM NaCl, 0.006% sodium azide, 0.03% BSA, and 40% glycerol.
      Applications
      ApplicationPlease note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Anti-Glycogen Synthase CT Antibody, rabbit detects level of Glycogen Synthase CT & has been published & validated for use in FC, IF, IP, WB, IH(P).
      Key Applications
      • Flow Cytometry
      • Immunofluorescence
      • Immunoprecipitation
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesSuggested Dilutions:
      Immunoblot Analysis: 1:50,000
      Immunoprecipitation: 1:150
      Flow Cytometry: 1:50
      Immunohistochemistry: 1:250-1:500
      Immunfluorescence Staining: 1:250-1:500
      Biological Information
      ImmunogenKLH-conjugated A synthetic peptide corresponding to residues in the C-terminus of the human glycogen synthase
      HostRabbit
      SpecificityRecognizes the C-term domain of Glycogen Synthase
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryGlycogen is a high molecular mass polysaccharide that serves as a repository of glucose for use in times of metabolic need. Glycogen synthase (EC 2.4.1.11) catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages (Pederson et al., 2004 [PubMed 15282316]).[supplied by OMIM]
      Gene Symbol
      • GYS1
      • Glycogen
      • GYS
      • GSY
      Purification MethodSerum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P13807 # Transfers the glycosyl residue from UDP-Glc to the nonreducing end of alpha-1,4-glucan.
      SIZE: 737 amino acids; 83786 Da
      SIMILARITY: SwissProt: P13807 ## Belongs to the mammalian/fungal glycogen synthase family.
      Molecular Weight85 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by immunoblot.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C from date of shipment.
      Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Glycogen Synthase CT - DAM1427458 DAM1427458
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2115545 2115545
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2136976 2136976
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2148880 2148880
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 0611045588 0611045588
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2048760 2048760
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2101955 2101955
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2210313 2210313
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2219264 2219264
      Anti-Glycogen Synthase CT, Rabbit Monoclonal - 2301390 2301390

      References

      Reference overviewPub Med ID
      Impact of genetic versus environmental factors on the control of muscle glycogen synthase activation in twins
      Poulsen, Pernille, et al
      Diabetes, 54:1289-96 (2005)  2005

      15855312 15855312
      Determinants of the nucleocytoplasmic shuttling of muscle glycogen synthase
      Cid, Emili, et al
      FEBS J, 272:3197-213 (2005)  2005

      15955076 15955076
      The primary defect in glycogen synthase activity is not based on increased glycogen synthase kinase-3alpha activity in diabetic myotubes.
      Gaster, Michael, et al.
      Biochem. Biophys. Res. Commun., 319: 1235-40 (2004)  2004

      Show Abstract
      15194499 15194499
      Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients
      Motoyama, Koka, et al
      Metab Clin Exp, 52:895-9 (2003)  2003

      12870167 12870167

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies