06-170 | Anti-Na+/K+ ATPase β-1 Antibody

200 µL  
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      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      RIP, WBRbPurifiedPolyclonal Antibody
      Catalogue Number06-170
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Na+/K+ ATPase β-1 Antibody
      Product Information
      Presentationwhole antiserum containing 0.05% sodium azide
      ApplicationAnti-Na+/K+ ATPase β-1 Antibody is an antibody against Na+/K+ ATPase β-1 for use in IP & WB.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenFusion protein corresponding to amino acids 152-340 of the beta 1 subunit
      SpecificityNa+/K+ ATPase β-1
      Species Reactivity
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.
      Gene Symbol
      • ATP1B1
      • MGC1798
      • adenosinetriphosphatase
      • ATP1B
      Purification MethodAntiserum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P05026 # This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
      SIZE: 303 amino acids; 35061 Da
      SUBUNIT: Composed of three subunits: alpha (catalytic), beta and gamma. Interacts with NKAIN1, NKAIN2 and NKAIN4 (By similarity).
      SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
      TISSUE SPECIFICITY: Found in most tissues.
      SIMILARITY: SwissProt: P05026 ## Belongs to the X(+)/potassium ATPases subunit beta family.
      Molecular Weight48/52kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on non-reduced brain or kidney microsomal preparations
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information




      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Na<sup>+</sup>/K<sup>+</sup> ATPase beta;-1 - 15436 15436
      Anti-Na<sup>+</sup>/K<sup>+</sup> ATPase beta;-1 - 15657 15657
      Anti-Na<sup>+</sup>/K<sup>+</sup> ATPase beta;-1 - 19997 19997


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      American journal of physiology. Heart and circulatory physiology  294  H613-21  2008

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      Human molecular genetics  16  2394-410  2007

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      Contraction and intracellular Ca(2+) handling in isolated skeletal muscle of rats with congestive heart failure.
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      Circulation research  88  1299-305  2001

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      Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice.
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      American journal of physiology. Regulatory, integrative and comparative physiology  278  R598-603  2000

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      Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes
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      J Biol Chem, 273:30344-51 (1998)  1998

      Immunoprecipitation, Immunoblotting (Western)9804797 9804797