05-143 | Anti-PLA2 Antibody, secretory

05-143
200 µg  
Retrieving price...
Price could not be retrieved
Minimum Quantity needs to be mulitiple of
Upon Order Completion More Information
You Saved ()
 
Request Pricing
Limited AvailabilityLimited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Click To Print This Page

      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, IHC, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue Number05-143
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-PLA2 Antibody, secretory
      References
      Product Information
      FormatPurified
      Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
      Applications
      ApplicationThis Anti-PLA2 Antibody, secretory is validated for use in ELISA, IH, WB for the detection of PLA2.
      Key Applications
      • ELISA
      • Immunohistochemistry
      • Western Blotting
      Biological Information
      ImmunogenPurified human PLA2; recognizes type II (secretory) PLA2.
      HostMouse
      Specificityhuman type II secretory PLA2 in sperm, disc and synovial fluid
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PLA2G2A
      • sPLA2
      • PLA2S
      • PLA2
      • MOM1
      • PLA2B
      • RASF-A
      • PLAS1
      • NPS-PLA2
      • PLA2L
      Purification MethodDEAE cellulose chromatography
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P14555 # Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides.
      COFACTOR: Binds 1 calcium ion per subunit.
      SIZE: 144 amino acids; 16083 Da
      SUBCELLULAR LOCATION: Membrane; Peripheral membrane protein.
      SIMILARITY: SwissProt: P14555 ## Belongs to the phospholipase A2 family.
      MISCELLANEOUS: Group II phospholipase A2 is found in many cells and also extracellularly. The membrane-bound and secreted forms are identical and are encoded by a single gene.
      Molecular Weight14/18 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated on PLA2 under non-reducing conditions
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-PLA2, secretory (mouse monoclonal IgG1) 2929116
      Anti-PLA2, secretory - 15601 15601
      Anti-PLA2, secretory - 19232 19232
      Anti-PLA2, secretory -2621184 2621184
      Anti-PLA2, secretory -2632984 2632984
      Anti-PLA2, secretory -2691197 2691197
      Anti-PLA2, secretory -2809905 2809905

      References

      Reference overviewApplicationPub Med ID
      TFF peptides and mucins are major components of dacryoliths.
      Friedrich P Paulsen, Ulrich Schaudig, Alexander Fabian, Dirk Ehrich, Saadettin Sel
      Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie  244  1160-70  2006

      Show Abstract
      16453128 16453128
      Detection of natural peptide antibiotics in human nasolacrimal ducts.
      F P Paulsen, T Pufe, U Schaudig, J Held-Feindt, J Lehmann, J M Schröder, B N Tillmann
      Investigative ophthalmology visual science  42  2157-63  2001

      Show Abstract
      11527925 11527925
      Secretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears
      Qu, X. D. and Lehrer, R. I.
      Infect Immun, 66:2791-7 (1998)  1998

      Immunoblotting (Western)9596749 9596749
      Angiotensin II type 2 receptor stimulation of neuronal delayed-rectifier potassium current involves phospholipase A2 and arachidonic acid
      Zhu, M., et al
      J Neurosci, 18:679-86 (1998)  1998

      Inhibits Activity/Function9425010 9425010
      Development and use of ELISA to quantify type II phospholipase A2 in normal and uremic serum
      Dorsam, G., et al
      Clin Chem, 41:862-6 (1995)  1995

      Enzyme Immunoassay (ELISA)7768005 7768005

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      05-143-KC Anti-PLA2, secretory (1mg) KC Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies