06-1007 | Anti-POPDC2 Antibody

06-1007
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, R, ChpWB, ICC, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue Number06-1007
      DescriptionAnti-POPDC2 Antibody
      Alternate Names
      • popeye domain containing 2
      • Popeye protein 2
      • popeye domain-containing protein 2
      • NET3
      Background InformationPOPDC2 (popeye domain-containing protein 2), also known as NET3, is a member of the POP family and is associated with striated and smooth muscle tissue development. POPDC2 is thought to be a plasma membrane protein containing three N-terminal transmembrane domains and a cytoplasmic carboxy terminus. POPDC2 is uniquely expressed in large numbers in the developing heart and could be used as a marker of myocardial differentiation. Recent research has found that POPDC2 is expressed in many different types of muscle and non-muscle cells during development.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human heart tissue lysate.
      Presentation0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-POPDC2 Antibody is a Rabbit Polyclonal Antibody for detection of POPDC2 also known as Popeye protein 2, NET3 & has been validated in WB, ICC & IHC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A representative lot was used by an independent laboratory in IH. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1)).

      Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in IC. (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1).

      Western Blot Analysis: A representative lot detected POPDC2 in mouse heart, rat heart tissues lysates.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human POPDC2.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      • Chimpanzee
      Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Chimpanzee based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummarySummary: This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle, and may have an important function in these tissues. [provided by RefSeq].
      Gene Symbol
      • POP2
      • POPDC2
      Purification MethodAffinity Purfied
      UniProt Number
      UniProt SummaryFUNCTION: May play an important role in heart development.

      SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).

      TISSUE SPECIFICITY: Expressed predominantly in the heart, and is also detected in the skeletal muscle.

      SEQUENCE SIMILARITIES: Belongs to the popeye family.

      SEQUENCE CAUTION: The sequence AAH26911.1 differs from that shown. Reason: Erroneous initiation.
      Molecular Weight~53 kDa observed. The observed higher molecular weight may be the result of glycolysation (Wilkie, G.S., et al. (2011). Mol Cell Proteomics. 10(1):M110.003129.).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human heart tissue lysate.

      Western Blot Analysis: 5 µg/mL of this antibody detected POPDC2 on 10 µg of human heart tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-POPDC2 - NRG1903978 NRG1903978
      Anti-POPDC2 -2691443 2691443
      Anti-POPDC2 -2716110 2716110

      References

      Reference overviewApplicationPub Med ID
      Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations.
      Wilkie, GS; Korfali, N; Swanson, SK; Malik, P; Srsen, V; Batrakou, DG; de las Heras, J; Zuleger, N; Kerr, AR; Florens, L; Schirmer, EC
      Molecular & cellular proteomics : MCP  10  M110.003129  2011

      Show Abstract Full Text Article
      Western Blotting20876400 20876400

      Brochure

      Title
      New Products: Volume 3, 2012