CBL402 | Anti-Papillomavirus 16 Late 1 Protein Antibody, clone CamVir-1

CBL402
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIF, IP, WB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL402
      ReplacesCBL403
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Papillomavirus 16 Late 1 Protein Antibody, clone CamVir-1
      Alternate Names
      • HPV-16 L1
      References
      Product Information
      FormatPurified
      PresentationThe monoclonal was purified by protein A affinity and is presented in phosphate buffered saline containing 10mM sodium azide and 1mg/mL bovine serum albumin.
      Applications
      ApplicationDetect Papillomavirus 16 Late 1 Protein using this Anti-Papillomavirus 16 Late 1 Protein Antibody, clone CamVir-1 validated for use in IF, IP, WB, IH(P).
      Key Applications
      • Immunofluorescence
      • Immunoprecipitation
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunocytochemistry: Detection of HPV in cervical smears and biopsies of cells fixed in acetone or paraformaldehyde.

      Immunoperoxidase staining of paraffin sections. HPV-16 infected cells show strong nuclear staining.

      Immunoprecipitation

      Western blotting

      Optimal working dilution must be determined by the end user.
      Biological Information
      ImmunogenAmino acids 198-531 of HPV16-L1 fused to beta-galactosidase.
      CloneCamVir-1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody recognizes late protein of human papilloma virus type 16. HPV-6 & -II positive biopsies gave negative results. On western blots CamVir-1 detects a 56 kDa band corresponding to the L1 protein as well as a 41 kDa non-specific band that is observed in a wide range of uninfected mammalian cells. This non-specific 41 kDa protein is absent by immunoprecipitation, immunofluorescence or immunoperoxidase. This may be a reflection of cross-reactivity between HPV-16 L1 and a cryptic epitope in mammalian cells that is only revealed following exhaustive denaturation.
      IsotypeIgG2a
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore in undiluted aliquots at -20°C for up to 12 months from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HPV-16 LATE 1 PROTEIN MONOCLONAL ANTIBODY - 2360870 2360870
      MOUSE ANTI-HPV-16 LATE 1 PROTEIN MONOCLONAL ANTIBODY - 2378764 2378764
      MOUSE ANTI-HPV-16 LATE 1 PROTEIN MONOCLONAL ANTIBODY - 2329139 2329139
      MOUSE ANTI-HPV-16 LATE 1 PROTEIN MONOCLONAL ANTIBODY - 2341902 2341902

      References

      Reference overviewPub Med ID
      Enhancement of capsid gene expression: preparing the human papillomavirus type 16 major structural gene L1 for DNA vaccination purposes
      Leder, C. et al.
      J Virol. , 75:9201-9209 (2001)  2001

      11533183 11533183
      Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus
      McLean, C. et al.
      J Clin Pathol. , 43:488-492 (1990)  1990

      2166093 2166093

      Data Sheet

      Title
      Anti-Human Papillomavirus 16 Late 1 Protein, clone CamVir-1 - Data Sheet

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      CBL402-K Anti-Papillomavirus 16 Late 1 Protein, Clone Camvir-1 Show Pricing & Availability
      CBL402-KC Mouse Anti-HPV-16 Late 1 Protein (1mg) KC Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies