529594 | Anti-Presenilin 2, Loop Domain (269-394) Rabbit pAb

529594
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.





      Recognizes the presenilin 2 holoprotein and its C-terminal fragments.
      Catalogue Number529594
      Brand Family Calbiochem®
      SynonymsAnti-αPS2-Loop
      References
      ReferencesThinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      Thinakaran, G., et al. 1997. J. Biol. Chem. 272, 28415.
      Thinakaran, G., et al. 1996. Neuron 17, 181.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunofluorescence
      Immunoprecipitation
      Application NotesImmunoblotting (1:2000-1:10,000, chemiluminescence)
      Immunofluorescence (1:250-1:500)
      Immunoprecipitation (1-2 µl/mg lysate protein)
      Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogena recombinant protein consisting of amino acids 269-394 of human presenilin 2 fused to GST
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      529594

      References

      Reference overview
      Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      Thinakaran, G., et al. 1997. J. Biol. Chem. 272, 28415.
      Thinakaran, G., et al. 1996. Neuron 17, 181.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-August-2007 RFH
      SynonymsAnti-αPS2-Loop
      ApplicationImmunoblotting (1:2000-1:10,000, chemiluminescence)
      Immunofluorescence (1:250-1:500)
      Immunoprecipitation (1-2 µl/mg lysate protein)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes full-length presenilin 2 and its C-terminal fragments.
      BackgroundMutations in the Presenilin 1 (PS1) and Presenilin 2 (PS2) genes have been associated with early-onset familial Alzheimer's disease.
      HostRabbit
      Immunogen speciesHuman
      Immunogena recombinant protein consisting of amino acids 269-394 of human presenilin 2 fused to GST
      IsotypeIgG
      Specieshuman, mouse
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesThinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
      Thinakaran, G., et al. 1997. J. Biol. Chem. 272, 28415.
      Thinakaran, G., et al. 1996. Neuron 17, 181.