CBL252 | Anti-Prostate Specific Antigen Antibody, clone A67-B/E3

CBL252
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, WB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL252
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Prostate Specific Antigen Antibody, clone A67-B/E3
      Alternate Names
      • PSA
      References
      Product Information
      FormatPurified
      PresentationThe monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
      Applications
      ApplicationThis Anti-Prostate Specific Antigen Antibody, clone A67-B/E3 is validated for use in ELISA, WB, IH(P) for the detection of Prostate Specific Antigen.
      Key Applications
      • ELISA
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesSuitable for PSA ELISA and western blotting assay development

      Immunohistochemistry on formalin-fixed paraffin-embedded sections after high temperature antigen retrieval in citrate buffer, pH 6.0.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      Immunogenp30 enriched preparation of human sperm plasma
      CloneA67-B/E3
      HostMouse
      SpecificityThe antibody recognizes PSA in ELISA and western blots

      FUSION PARTNER: x63-Ag.8.653 myeloma cell line
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
      Gene Symbol
      • KLK3
      • Seminin
      • seminin
      • APS
      • hK3
      • PSA
      • semenogelase
      • Semenogelase
      • gamma-seminoprotein
      • KLK2A1
      • Gamma-seminoprotein
      • EC 3.4.21.77
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P07288 # Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
      SIZE: 261 amino acids; 28741 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P07288 ## Belongs to the peptidase S1 family. Kallikrein subfamily. & Contains 1 peptidase S1 domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsFor use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies