MABS747 | Anti-RBP4, clone EPR5878, Rabbit Monoclonal Antibody

MABS747
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbUnpurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS747
      DescriptionAnti-RBP4, clone EPR5878, Rabbit Monoclonal Antibody
      Alternate Names
      • Retinol-binding protein 4
      • Plasma retinol-binding protein
      • PRBP
      • RBP
      Background InformationRetinol-binding protein 4, also known as Plasma retinol-binding protein or PRBP or RBP, and encoded by RBP4, is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. Mutations in RBP4 have been associated with retinal dystrophy, iris coloboma, and comedogenic acne syndrome.
      References
      Product Information
      FormatUnpurified
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      Applications
      ApplicationThis Anti-RBP4, clone EPR5878, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of RBP4.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:100-250 dilution from a representative lot detected RBP4 in human kidney tissue.

      Produced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human RBP4.
      CloneEPR5878
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • RBP4
      • PRO2222
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~23 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human plasma, human fetal liver, and HepG2 lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected RBP4 in human plasma, human fetal liver, and HepG2 lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies