05-853 | Anti-Rab11 Antibody, clone 47

05-853
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      Ca, Ch, H, M, Mk, RIF, WBMAffinity PurifiedMonoclonal Antibody
      Description
      Catalogue Number05-853
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-Rab11 Antibody, clone 47
      References
      Product Information
      FormatAffinity Purified
      Applications
      ApplicationThis Anti-Rab11 Antibody, clone 47 is validated for use in IF, WB for the detection of Rab11.
      Key Applications
      • Immunofluorescence
      • Western Blotting
      Application NotesThis antibody has been reported by an independent laboratory to produce positive staining for Rab11 in rat adrenal gland (Steiner, P., et al., J. Cell. Biol. 157: 1197-1209, 2002)
      Biological Information
      ImmunogenRecombinant human Rab11 containing amino acids 86-207
      Cloneclone 47
      HostMouse
      SpecificityRab11
      IsotypeIgG2a
      Species Reactivity
      • Canine
      • Chicken
      • Human
      • Mouse
      • Monkey
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport.
      Gene Symbol
      • RAB11A
      • Rab-11
      • RAB11
      • MGC1490
      • YL8
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P62491 # Modulates endosomal trafficking (By similarity).
      SIZE: 216 amino acids; 24394 Da
      SUBUNIT: Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Binds RIP11 and STXBP6 (By similarity).
      SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
      SIMILARITY: SwissProt: P62491 ## Belongs to the small GTPase superfamily. Rab family.
      Molecular Weight24kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated by immunoblot in RIPA lysates from HEK293 and HeLa cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -20°C from date of shipment
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Rab11, clone 47 (mouse monoclonal IgG2a) - 2196737 2196737
      Anti-Rab11, clone 47 - 2011576 2011576
      Anti-Rab11, clone 47 - 27149 27149
      Anti-Rab11, clone 47 - DAM1598785 DAM1598785
      Anti-Rab11, clone 47 - DAM1614912 DAM1614912
      Anti-Rab11, clone 47 - DAM1661047 DAM1661047
      Anti-Rab11, clone 47 - DAM1734759 DAM1734759
      Anti-Rab11, clone 47 - DAM1776426 DAM1776426
      Anti-Rab11, clone 47 - JBC1363104 JBC1363104
      Anti-Rab11, clone 47 - JBC1839877 JBC1839877

      References

      Reference overviewApplicationPub Med ID
      Prolonged morphine treatment alters δ opioid receptor post-internalization trafficking.
      Ong, EW; Xue, L; Olmstead, MC; Cahill, CM
      British journal of pharmacology  172  615-29  2015

      Show Abstract
      24819092 24819092
      Secretion of soluble vascular endothelial growth factor receptor 1 (sVEGFR1/sFlt1) requires Arf1, Arf6, and Rab11 GTPases.
      Jung, JJ; Tiwari, A; Inamdar, SM; Thomas, CP; Goel, A; Choudhury, A
      PloS one  7  e44572  2012

      Show Abstract
      22962618 22962618
      Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins.
      Junutula, Jagath R, et al.
      J. Biol. Chem., 279: 33430-7 (2004)  2004

      Show Abstract
      15173169 15173169
      Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases.
      Seachrist, Jennifer L and Ferguson, Stephen S G
      Life Sci., 74: 225-35 (2003)  2003

      Show Abstract
      14607250 14607250
      Regulation of G-protein-coupled receptor activity by rab GTPases.
      Rosenfeld, Jennifer L, et al.
      Recept. Channels, 8: 87-97 (2002)  2002

      Show Abstract
      12448790 12448790
      Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells.
      Woods, Alison J, et al.
      J. Biol. Chem., 277: 6428-37 (2002)  2002

      Show Abstract
      Immunoblotting (Western)11704675 11704675
      Modulation of receptor cycling by neuron-enriched endosomal protein of 21 kD
      Steiner, P., et al
      J Cell Biol, 157:1197-209 (2002)  2002

      Immunoblotting (Western), Immunofluorescence12070131 12070131
      Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann-Pick C cells.
      Choudhury, Amit, et al.
      J. Clin. Invest., 109: 1541-50 (2002)  2002

      Show Abstract
      Immunoblotting (Western)12070301 12070301
      Regulation of membrane transport through the endocytic pathway by rabGTPases.
      Mohrmann, K and van der Sluijs, P
      Mol. Membr. Biol., 16: 81-7 (1999)  1999

      Show Abstract
      10332741 10332741

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      Categories

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