05-515MG | Anti-acetyl-Lysine Antibody, clone 4G12

05-515MG
1 mg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AIP, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue Number05-515MG
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-acetyl-Lysine Antibody, clone 4G12
      References
      Product Information
      FormatPurified
      Presentation1mg of protein G purified mouse IgG in 0.75 mL of PBS.
      Applications
      ApplicationAnti-acetyl-Lysine Antibody, clone 4G12 is a high quality Mouse Monoclonal Antibody for the detection of acetyl-Lysine & has been validated in IP & WB.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenMixture of chemically acetylated antigens; recognizes numerous proteins acetylated on a lysine, most prominently on histones
      Clone4G12
      HostMouse
      Specificityacetylated lysine-containing proteins including histones
      IsotypeIgG
      Species Reactivity
      • All
      Antibody TypeMonoclonal Antibody
      Modifications
      • Acetylation
      Purification MethodProtein G Purified
      Molecular Weightvaries depending upon the protein being detected
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on acid-extracted proteins from sodium butyrate (5mM) treated HeLa cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-Acetyl-Lysine, clone 4G12 - 26626 26626
      Anti-Acetyl-Lysine, clone 4G12 - 29636 29636
      Anti-Acetyl-Lysine, clone 4G12 - 31383 31383
      Anti-acetyl-Lysine, clone 4G12 (mouse monoclonal IgG) - 2080304 2080304

      References

      Reference overviewPub Med ID
      p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage.
      Liu, L, et al.
      Mol. Cell. Biol., 19: 1202-9 (1999)  1999

      Show Abstract
      9891054 9891054
      Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome.
      Munshi, N, et al.
      Mol. Cell, 2: 457-67 (1998)  1998

      Show Abstract
      9809067 9809067
      Acetylation of general transcription factors by histone acetyltransferases.
      Imhof, A, et al.
      Curr. Biol., 7: 689-92 (1997)  1997

      9285713 9285713

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      05-515 Anti-acetyl-Lysine Antibody, clone 4G12 Show Pricing & Availability

      Alternative Format

      Catalogue Number Description  
      16-272 Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate Show Pricing & Availability

      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies