05-627 | Anti-gC1qR Antibody, clone 74.5.2

05-627
200 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, FC, IF, WBMAscitesMonoclonal Antibody
      Description
      Catalogue Number05-627
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-gC1qR Antibody, clone 74.5.2
      References
      Product Information
      FormatAscites
      Presentationmouse ascites with 30% glycerol
      Applications
      ApplicationAnti-gC1qR Antibody, clone 74.5.2 detects level of gC1qR & has been published & validated for use in ELISA, FC, IF & WB.
      Key Applications
      • ELISA
      • Flow Cytometry
      • Immunofluorescence
      • Western Blotting
      Biological Information
      ImmunogenGST fusion protein corresponding to residues 74-282 of the mature form of human gC1qR. The epitope has been mapped to residues 204-218
      Clone74.5.2
      HostMouse
      Specificitymature form and the truncated form of gC1qR
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.
      Gene Symbol
      • C1QBP
      • C1qBP
      • p33
      • gC1Q-R
      • GC1QBP
      • gC1qR
      • GC1Q-R
      • HABP1
      • SF2P32
      • SF2p32
      • p32
      Purification MethodAscites
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q07021 # Not known. Binds to the globular heads of C1Q thus inhibiting C1 activation.
      SIZE: 282 amino acids; 31362 Da
      SUBUNIT: Interacts with Rubella virus capsid protein.
      SUBCELLULAR LOCATION: Mitochondrion matrix.
      SIMILARITY: SwissProt: Q07021 ## Belongs to the MAM33 family.
      Molecular Weight33kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on RIPA lysates from Raji cells
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2121516 2121516
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2030018 2030018
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2050239 2050239
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2091754 2091754
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2187379 2187379
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2197197 2197197
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2208778 2208778
      Anti-gC1qR, clone 74.5.2 (mouse ascites) - 2320056 2320056
      Anti-gC1qR, clone 74.5.2 - 22001 22001
      Anti-gC1qR, clone 74.5.2 - DAM1687512 DAM1687512

      References

      Reference overviewPub Med ID
      Identification of functional domains on gC1Q-R, a cell surface protein that binds to the globular "heads" of C1Q, using monoclonal antibodies and synthetic peptides.
      Ghebrehiwet, B, et al.
      Hybridoma, 15: 333-42 (1996)  1996

      Show Abstract
      8913782 8913782

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies