12-423 | Casein Kinase 1 Substrate Peptide

12-423
1 mg  
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      Overview

      Replacement Information
      Description
      Catalogue Number12-423
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCasein Kinase 1 Substrate Peptide
      References
      Product Information
      Presentationsterile, distilled water
      Applications
      Key Applications
      • Kinase Assay
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
      Gene Symbol
      • CSNK2B
      • Phosvitin
      • CK2B
      • CSK2B
      • MGC138224
      • MGC138222
      • CK2N
      • G5a
      • phosvitin
      • G5A
      Protein TargetCK1
      Target Sub-FamilyCK1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P67870 # Participates in Wnt signaling (By similarity). Plays a complex role in regulating the basal catalytic activity of the alpha subunit.
      SIZE: 215 amino acids; 24942 Da
      SUBUNIT: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation.
      PTM: Phosphorylated by alpha subunit.
      SIMILARITY: SwissProt: P67870 ## Belongs to the casein kinase 2 subunit beta family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceRoutinely evaluated as a substrate for Casein Kinase I.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions2 years at -20°C
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificates of Analysis

      TitleLot Number
      Casein Kinase 1Substrate Peptide - DAM1687555 DAM1687555
      Casein Kinase 1Substrate Peptide - DAM1770331 DAM1770331
      Casein Kinase 1Substrate Peptide - NG1938981 NG1938981

      References

      Reference overviewPub Med ID
      Design and synthesis of two new peptide substrates for the specific and sensitive monitoring of casein kinases-1 and -2.
      Marin, O, et al.
      Biochem. Biophys. Res. Commun., 198: 898-905 (1994)  1994

      Show Abstract
      8117294 8117294

      Related Products & Applications

      Product Families

      Categories

      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates
      Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates