Durapore 0.45 µm Hydrophilic Cartridge Filter

The superior solution for extending the life of downstream sterilizing filters by removing colloidal and particulate contaminants

Overview

Specifications

Ordering Information

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Durapore Cartridge with Prefilter Layer · Code 0, 2-222 O-ring Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL01TP310 in. (25 cm) Show Pricing & Availability
CVHL02TP320 in. (50 cm) Show Pricing & Availability
CVHL03TP330 in. (75 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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Durapore Cartridge without Prefilter Layer · Code 0, 2-222 O-ring Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL01PP310 in. (25 cm) Show Pricing & Availability
CVHL02PP320 in. (50 cm) Show Pricing & Availability
CVHL03PP330 in. (75 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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Durapore Cartridge with Prefilter Layer · Code 5, 2-222 O-ring w/spear Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL51TP310 in. (25 cm) Show Pricing & Availability
CVHL52TP320 in. (50 cm) Show Pricing & Availability
CVHL53TP330 in. (75 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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Durapore Cartridge without Prefilter Layer · Code 5, 2-222 O-ring w/spear Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL51PP310 in. (25 cm) Show Pricing & Availability
CVHL52PP320 in. (50 cm) Show Pricing & Availability
CVHL53PP330 in. (75 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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Durapore Cartridge with Prefilter Layer · Code 7, 2-226 O-ring w/locking-tabs and spear Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL71TP310 in. (25 cm) Show Pricing & Availability
CVHL72TP320 in. (50 cm) Show Pricing & Availability
CVHL73TP330 in. (75 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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Durapore Cartridge without Prefilter Layer · Code 7, 2-226 O-ring w/locking-tabs and spear Clear Sorting & Filtering
Catalogue Numbericon Cartridge Nominal Lengthicon
CVHL71PP310 in. (25 cm) Show Pricing & Availability
CVHL72PP320 in. (50 cm) Show Pricing & Availability
CVHL73PP330 in. (75 cm) Show Pricing & Availability
CVHL75PP15 in. (12.5 cm) Show Pricing & Availability

Packaged 3 cartridges per box

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    Documentation

    Brochure

    Title
    Evaluation of Filtration Products in the Production of Adenovirus Candidates Used in Vaccine Production: Overview and Case Study

    Technical Info

    Title
    Bubble Point Test Method Using Durapore® 0.45 um Hydrophilic Membrane with 70/30 IPA, HUMP 047 00, XEIT110 00, XX44 047 00, AN1421EN00

    Data Sheet

    Title
    Durapore® 0.45 μm Hydrophilic Filters

    FAQ

    QuestionAnswer
    What is the compatibility of Durapore with high pH solutions?The upper recommended pH limit for Durapore membranes is 10. At pH >10, the hydrophilization layer of the membrane may become subject to hydrolysis. The extent of hydrolysis is a function of time, temperature , concentration and time of exposure. Upon exposure to high pH, the hydrophylization layer can swell which could result in a loss of permeability or flux. The hydrolysis of the hydrophilic layer will also lead to increased extractables from the membrane.
    What are Millipore's general recommendations for filtering high pH solutions?For applications involving pH > 10, Millipore recommends the use or our PES membranes Express SHF or Express SHC. For information on these filters :

    Express SHF: http://www.millipore.com/catalogue.nsf/docs/C8873
    Express SHC: http://www.millipore.com/catalogue.nsf/docs/C9146
    How can I differentiate filter plugging due to air bubbles, particulates, surface tension, inappropriate filter size, etc.?Air locking will occur when filtration is initiated without adequate venting or when air bubbles become trapped in fluid lines. Air will pass easily through a dry hydrophillic or hydrophobic filter. However, when a filter is wet and air is applied to a surface, the air will remain until it is manually moved upstream by venting or until the bubble point of the filter is reached. Bubble point is defined as the pressure at which gas displaces liquid for the largest set of filter pores and is able to flow through the pores. Air locking reduces the effective filtration area of the filter and thus reduces the flow rate.

    Surface tension refers to the strong cohesive forces present between molecules at the surface of a liquid. The higher the surface tension, the more force is required to force fluid through the membrane..

    Innapropriate filter size will can cause a filter to plug prematurely. Filter pore size is chosen based on the application. If the application requires a sterile fluid, than a 0.22 micron membrane would be used for standard solutions that have bacterial bioburden. A 0.1 micron filter would be used for applications where mycoplasma is a concern. Where virus contamination is a concern, ultrafiltration would be required. The selection of a filter pore size that is smaller than that required for the application will cause a decrease in filter capacity and an increase in cost.
    Are any of the prefilters compatable with ozone?No. The Mykrolis corporation has ozone compatible filters. Please contact them for help with your specific application. They can be reached at 877-695-7654.

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    Categories

    Biopharmaceutical Manufacturing > Upstream Processing > Bioburden Reduction / Particulate Control > Membrane based > Durapore