01-102 | Epidermal growth factor (EGF), receptor grade

100 µg  
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      Replacement Information

      Key Spec Table

      Key ApplicationsSpeciesSourcePurity
      CULTMouseMouse submaxillary glands≥99% by SDS-PAGE and Coomassie blue staining.
      Catalogue Number01-102
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionEpidermal growth factor (EGF), receptor grade
      Product Information
      PresentationLyophilized from 10mM sodium acetate
      ApplicationThis Epidermal growth factor (EGF), receptor grade product is available in a 100 µg format.
      Key Applications
      • Cell Culture
      Biological Information
      Purity≥99% by SDS-PAGE and Coomassie blue staining.
      SourceMouse submaxillary glands
      Entrez Gene Number
      Entrez Gene SummaryEpidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.
      Gene Symbol
      • EGF
      • URG
      • urogastrone
      Purification MethodSterilized through a 0.2 micron membrane filter
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01133 # EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.
      SIZE: 1207 amino acids; 133946 Da
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      SIMILARITY: SwissProt: P01133 ## Contains 9 EGF-like domains. & Contains 9 LDL-receptor class B repeats.
      Stem Cell Type
      • Mouse Embryonic Stem Cells
      • Neural Stem Cells
      • Mesenchymal Stem Cells
      • Induced Pluripotent Stem Cells
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated in a 5-day growth assay using human foreskin fibroblasts
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsLyophilized: Stable for 2 years at 4°C from date of shipment.
      Rehydrated: Stable for 3 months at -20°C. Aliquot to avoid repeated freezing and thawing.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information


      Certificates of Analysis

      TitleLot Number
      EGF 2478911
      EGF 2470335
      EGF (receptor grade) - 2145049 2145049
      EGF (receptor grade) -
      EGF (receptor grade) - 2090503 2090503
      EGF (receptor grade) - 2210330 2210330
      EGF (receptor grade) - 2342851 2342851
      EGF (receptor grade) -2739396 2739396
      EGF - 2483148 2483148
      EGF - DAM1546222 DAM1546222


      Reference overviewApplicationPub Med ID
      Role of Rho family proteins in phospholipase D activation by growth factors.
      Hess, J A, et al.
      J. Biol. Chem., 272: 1615-20 (1997)  1997

      Show Abstract
      Cell Stimulation8999836 8999836
      Cell shape-dependent regulation of protein 4.1 alternative pre-mRNA splicing in mammary epithelial cells.
      Schischmanoff, P O, et al.
      J. Biol. Chem., 272: 10254-9 (1997)  1997

      Show Abstract
      Cell Culture9092575 9092575
      Sequence-independent inhibition of in vitro vascular smooth muscle cell proliferation, migration, and in vivo neointimal formation by phosphorothioate oligodeoxynucleotides.
      Wang, W, et al.
      J. Clin. Invest., 98: 443-50 (1996)  1996

      Show Abstract
      Cell Culture8755655 8755655
      Epidermal growth factor.
      Cohen, S
      In Vitro Cell. Dev. Biol., 23: 239-46 (1987)  1987

      3553146 3553146

      Related Products & Applications

      Product Families


      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors