AP500 | Goat Anti-Mouse IgM µ chain Antibody, Species Adsorbed

AP500
1 mg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberAP500
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionGoat Anti-Mouse IgM µ chain Antibody, Species Adsorbed
      Background InformationIgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.
      References
      Product Information
      FormatUnconjugated
      PresentationPurified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 1.0 mL of 100 mM borate buffered saline, pH 8.2.
      Applications
      ApplicationThis Goat anti-Mouse IgM µ chain Antibody, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM µ chain.
      Key Applications
      • ELISA
      Biological Information
      ImmunogenPrepared from purified mouse IgM µ chain. Pooled antisera from goats hyperimmunized with mouse IgM paraproteins.
      EpitopeIgM µ chain
      Concentration1 mg/mL
      HostGoat
      SpecificityThe antibody reacts with the heavy chain of mouse IgM as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.
      Species Reactivity
      • Mouse
      Species Reactivity NoteReacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.
      Antibody TypePolyclonal Antibody
      Purification MethodAffinity Chromatography
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      GOAT ANTI-MOUSE IgM m CHAIN SPECIFIC SPECIES ADSORBED (HUMAN) - 2068542 2068542
      GOAT ANTI-MOUSE IgM m CHAIN SPECIFIC SPECIES ADSORBED (HUMAN) POLYCLONAL ANTIBODY - 2271126 2271126
      GOAT ANTI-MOUSE IgM u CHAIN SPECIFIC SPECIES ADSORBED (HUMAN) POLYCLONAL ANTIBODY 2935524
      GOAT ANTI-MOUSE IgM μ CHAIN SPECIFIC -2605596 2605596

      References

      Reference overviewPub Med ID
      Glu121-Lys319 salt bridge between catalytic and N-terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N.
      Rajesh Gumpena,Chandan Kishor,Roopa Jones Ganji,Nishant Jain,Anthony Addlagatta
      Protein science : a publication of the Protein Society  21  2012

      Show Abstract
      22411732 22411732

      Data Sheet

      Title
      GOAT ANTI-MOUSE IgM μ CHAIN SPECIFIC SPECIES ADSORBED (HUMAN) POLYCLONAL ANTIBODY

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      Categories

      Life Science Research > Antibodies and Assays > Secondary Antibodies