14-1061 | Human Recombinant Hp1γ (CBX3)

14-1061
25 µg  
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      Overview

      Replacement Information
      Description
      Catalogue Number14-1061
      Trade Name
      • Upstate
      DescriptionHuman Recombinant Hp1γ (CBX3)
      OverviewFull-length human recombinant Hp1γ (CBX3) expressed in E. Coli and purified by Fast Protein Liquid Chromatography (FPLC).
      Background InformationHp1γ (CBX3) is nuclear protein with a calculated molecular weight of 20.8 kDa. This protein associates with euchromatin and is largely excluded from constitutive heterochromatin. CBX3 recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In vivo Hp1 (CBX3) seems to be involved in transcriptional silencing in heterochromatin-like complexes and may also be associated with microtubules and mitotic poles during mitosis.
      References
      Product Information
      PresentationRecombinant protein in a buffer containing 20mM Tris-Cl pH 7.6, 1mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5mM PMSF and 1mM DTT.
      Applications
      ApplicationHuman Recombinant Hp1γ (CBX3) protein expressed in E. Coli & purified by Fast Protein Liquid Chromatography (FPLC).
      Biological Information
      Concentration0.5 µg/µL
      HostE. coli
      PurityGreater than 98% purity by SDS PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable at -80ºC for 1 year from date of receipt.
      Packaging Information
      Material Size25 µg
      Transport Information
      Supplemental Information
      Specifications