14-1065 | Human Recombinant MBD4 (Active Full Length)

14-1065
10 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      Enzyme Assays
      Description
      Catalogue Number14-1065
      DescriptionHuman Recombinant MBD4 (Active Full Length)
      OverviewHuman full length recombinant N-terminal His-tagged MBD4 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).
      Background InformationMethyl-CpG-binding domain protein 4 (MBD4) is a mismatch-specific DNA N-glycosylase involved in DNA repair. MBD4 has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. MBD4 can also remove uracil or 5-fluorouracil in G:U mismatches. MBD4 has been shown to interact with MLH1 and FADD.
      References
      Product Information
      PresentationIn a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.
      Applications
      ApplicationHuman full length recombinant N-terminal His-tagged MBD4 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to have DNA glycosylase activity.
      Key Applications
      • Enzyme Assays
      Biological Information
      Concentration0.5 µg/µL
      Molecular Weight70 kDa including histidine tag
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable at -80ºC for 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Proteins and Enzymes > Other Enzymes