117198 | LEUCOGNOST® NASDCL new

117198
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      Overview

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      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      1171980001
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          Fibre case 1 set
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          Description
          Catalogue Number117198
          OverviewThe enzyme cytochemistry leukemia detection kit LEUCOGNOST® NASDCL new enables the semi-quantitative localization of naphthol AS-D chloroacetate esterase activity in leukocytes via the enzymatic hydrolysis of naphthol AS-D chloroacetate to a naphthol compound. This product, in turn, reacts with a diazonium salt to form an insoluble red-violet dye. The kit is registered as a CE / IVD product for applications in both cellular and tissue diagnostics and is sufficient for 12 staining applications with up to 16 slides each.

          It features a new and improved formulation which produces a subtle coloration of cytoplasmic granules within granulopoietic cells, thus making detection of acute myeloblastic leukemia (AML) easier. This new version of the kit has been developed and characterized, to achieve a high degree of standardization using both native blood and bone marrow smears.

          LEUCOGNOST® NASDCL new reacts clearly with both mature and immature granulocytes. Intense enzyme activity can also be detected in myelocytes, metamyelocytes, stab cells and mast cells. Activity may also be detected in myeloblastic leukemia cells, promyelocytes and Auer bodies. Monocytes are rarely reactive. Eosinophils, basophils, megakaryocytes, lymphocytes, plasma cells and red cell precursors show no or at most very weak reaction.
          References
          Product Information
          HS Code3822 00 00
          Applications
          Biological Information
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Hazard Pictogram(s)
          Precautionary Statement(s)P201: Obtain special instructions before use.
          P210: Keep away from heat.
          P273: Avoid release to the environment.
          P280: Wear protective gloves.
          P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
          P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
          P308 + P313: IF exposed or concerned: Get medical advice/ attention.
          Signal WordDanger
          Storage class3 Flammable liquids
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +8°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3316 , 9, II
          Declaration (transport by air) IATA-DGRUN 3316 , 9, II
          Declaration (transport by sea) IMDG-CodeUN 3316 , 9, II
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1171980001 Fibre casePDF Specification Document

          Brochure

          Title
          LEUCOGNOST® NASDCL new

          Instructions for Use

          Title
          117198 LEUCOGNOST® NASDCL new - Detection of naphthol AS-D chloroacetate esterase in granulocytes
          117198 LEUCOGNOST® NASDCL Neu - Nachweis der Naphthol-AS-D-Chloracetat-Esterase in Granulozyten
          117198 LEUCOGNOST® NASDCL neo - Misura della esterasi naftolo-AS-D-cloroacetato
          117198 LEUCOGNOST® NASDCL nuevo - detección de naftol-AS-D-cloroacetato- esterasa en granulocitos
          117198 LEUCOGNOST® NASDCL néo - Mise en évidence de naphtol AS-D chloracétate