FCMAB167F | Milli-Mark Anti-CD2-FITC Antibody, clone MT910

FCMAB167F
100 tests  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMFITCMonoclonal Antibody
      Description
      Catalogue NumberFCMAB167F
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark Anti-CD2-FITC Antibody, clone MT910
      Alternate Names
      • CD2R, E-rosette receptor, T11, lymphocyte-function antigen-2 (LFA-2) (2).
      Background InformationCD2 is a 50 kDa single-chain type I transmembrane glycoprotein, originally defined as the sheep erythrocyte receptor. CD2 primarily binds CD58 on antigen-presenting cells and induces costimulatory signals in T cells (Kato, 2002). CD2 is one of the earliest T-cell lineage-restricted antigens to appear during T-cell differentiation, and it is expressed on most thymocytes, peripheral T cells and NK cells. Some B-cell non-Hodgkin lymphomas show aberrant expression of CD2. This may represent clonal expansion of CD2+ B lymphocytes that normally constitute a small fraction of peripheral B lymphocytes (Kaleem, 2001). Additionally, aberrant CD2 expression has been found in some acute myeloid leukaemias almost exclusively restricted to the M3 and M4Eo variants (Thalhammer-Scherrer, 2002).
      References
      Product Information
      FormatFITC
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1k conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2
      Applications
      ApplicationMilli-Mark Anti-CD2-FITC Antibody, clone MT910 detects level of CD2 & has been published & validated for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      CloneMT910
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD2 antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight50 kDa (Kato, 2002)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using Human Lymphocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies