481105 | Neurotoxin Type B, Clostridium botulinum

481105
  
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      Overview

      Replacement Information
      Description
      OverviewPotent neurotoxin that acts on the presynaptic ends of peripheral cholinergic nerve endings and blocks the release of acetylcholine.
      Catalogue Number481105
      Brand Family Calbiochem®
      References
      ReferencesSathyamoorthy, V., and DasGupta, B.R. 1985. J. Biol. Chem. 260, 10461. Gill, D.M. 1982. Microbiol. Rev. 46, 86.
      Product Information
      DeclarationNot available for sale outside of the United States.
      FormSolid
      FormulationLyophilized from 1.25% lactose solution.
      Applications
      Biological Information
      PuritySingle band of 150 kDa (non-reducing), two bands of 100 kDa and 50 kDa (reducing) by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 26/27/28

      Very toxic by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36/37/39-45

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      End use certificateY
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      SDS

      Title

      Safety Data Sheet (SDS) 

      Certificates of Analysis

      TitleLot Number
      481105

      References

      Reference overview
      Sathyamoorthy, V., and DasGupta, B.R. 1985. J. Biol. Chem. 260, 10461. Gill, D.M. 1982. Microbiol. Rev. 46, 86.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      DescriptionPotent neurotoxin that acts on peripheral cholinergic nerve endings by binding at the presynaptic membrane, blocking the release of the neurotransmitter acetylcholine.
      FormSolid
      FormulationLyophilized from 1.25% lactose solution.
      PuritySingle band of 150 kDa (non-reducing), two bands of 100 kDa and 50 kDa (reducing) by SDS-PAGE
      SolubilityReconstitute in 100 µl sterile, distilled H₂O.
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Highly Toxic
      ReferencesSathyamoorthy, V., and DasGupta, B.R. 1985. J. Biol. Chem. 260, 10461. Gill, D.M. 1982. Microbiol. Rev. 46, 86.