524737 | Phosphodiesterase 4C2, His•Tag®, Human, Recombinant, S. frugiperda

524737
  
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      Overview

      Replacement Information

      Key Spec Table

      Description
      Overview

      This product has been discontinued.





      Full-length, recombinant, human phosphodiesterdase 4C2 (accession no. U88712) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified preparation of the catalytically active enzyme.
      Catalogue Number524737
      Brand Family Calbiochem®
      SynonymsPDE4C2, cAMP-Specific Phosphodiesterase 4C2
      Application Data
      Phosphodiesterase 4C2 was treated with increasing concentration of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 7.87 µM.
      References
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Sullivan, M., et al. 1999. Cell Signal. 11, 735.
      Engels, P., et al. 1995. FEBS Lett. 358, 305.
      Product Information
      Activity≥ 0.5 units/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-HCl, 0.1% NP-40, pH 8.3.
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificates of Analysis

      TitleLot Number
      524737

      References

      Reference overview
      Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Sullivan, M., et al. 1999. Cell Signal. 11, 735.
      Engels, P., et al. 1995. FEBS Lett. 358, 305.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-March-2009 JSW
      SynonymsPDE4C2, cAMP-Specific Phosphodiesterase 4C2
      Application Data
      Phosphodiesterase 4C2 was treated with increasing concentration of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 7.87 µM.
      DescriptionFull-length, recombinant, human phosphodiesterdase 4C2 (accession no. U88712) fused at the N-terminus to a His•Tag® sequence and expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified preparation of the catalytically active enzyme.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-HCl, 0.1% NP-40, pH 8.3.
      Activity≥ 0.5 units/µl
      Unit definitionOne unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      Storage ≤ -70°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesGibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39.
      Sullivan, M., et al. 1999. Cell Signal. 11, 735.
      Engels, P., et al. 1995. FEBS Lett. 358, 305.