96-well strip plate  
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      Key Spec Table

      Analytes AvailableSpecies ReactivityKey Applications
      Catalogue NumberEZRIL17A
      DescriptionRat IL-17A ELISA Kit, EZRIL17A
      Background InformationRat IL-17A (other synonyms include IL-17, Cytotoxic T Lymphocyte-Associated Antigen-8 [CTLA-8]) is a founding member of the IL-17 family of cytokines. IL-17 is mainly produced by Th17 cells, a small subset of T helper cells. IL-17 exhibits multiple biological activities including the induction of various proinflammatory cytokines and chemokines such as IL-6, IL-8, G-CSF, GM-CSF, GRO-α, and MCP-1 on a variety of cell types. IL-17 is also involved in the activation of NF-kB and costimulation of T cell proliferation. As a result of these roles, IL-17 has been linked to many immune and autoimmune-related diseases including rheumatoid arthritis, asthma, lupus and multiple sclerosis.

      The ELISA kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with 96-well strip-plates that are pre-coated with a capture antibody.

      The ELISA kits with pre-coated plates are specifically designed for the accurate quantification of analytes from cell culture supernatant, serum, plasma or other body fluids. All kits are analytically validated and provide ready-to-use reagents.
      Product Information
      Precision, %
      • Intra-assay: <10 %
      • Inter-assay: <15 %
      ApplicationThe Rat IL-17A ELISA kit is a S&wich Enzyme-Linked Immuno-sorbent Assay (ELISA) with 96 well strip plates that are pre-coated with a capture antibody.
      Key Applications
      • ELISA
      Biological Information
      SpecificityThis kit cross-reacts with mouse IL-17A. Recombinant mouse IL-17A/F shows approximately 2.2% cross-reactivity in this assay.

      No cross reactivity was observed when this kit was used to analyze the following recombinant cytokines/chemokines at up to 50 ng/mL.

      Human: IL-1b, IL-2, IL-6, IL-8, IL-10, IL-11, IL-12 (p40), IL-13, IL-15, IL- 17A, IL-17A/F, IL-17E, IL-17F, IL-23, IL-27, IL-32, IFN-g, TSLP

      Mouse: IL-2, IL-10, IL-12 (p70), IL-13, IL-17B, IL-17E, IL-17F, IL-22, IL- 33, FGF-basic, IFN-g, MCP-1, SCF, TNF-a

      Rat: IL-1b, IL-2, IL-5, IL-6, IL-9, IL-10, IL-12 (p40), IL-13, IL-17E, IL-17F, IL-18, IL-22, IL-23, IL-33, CCL20, GM-CSF, IFN-g, KC, MCP-1, RANTES
      Species Reactivity
      • Rat
      Analytes Available
      • IL-17A
      • 106%
      Physicochemical Information
      • 4 pg/mL
      Linearity of DilutionContact Technical Service for this information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information

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      Life Science Research > Protein Detection and Quantification > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits
      Life Science Research > Antibodies and Assays > Immunoassays > Enzyme-linked Immunosorbent Assay (ELISA) > Complete ELISA Kits