03-0127-00 | SMC™ Mouse IL-22 Discovery Immunoassay Kit

03-0127-00
96-well strip plate  
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      Overview

      Replacement Information

      Key Spec Table

      Analytes AvailableSpecies ReactivityKey Applications
      IL-22MSingle Molecule Counting
      Description
      Catalogue Number03-0127-00
      Trade Name
      • SMC™
      DescriptionSMC™ Mouse IL-22 Discovery Immunoassay Kit
      OverviewThe SMC™ Mouse IL-22 Discovery Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
      Background InformationInterleukin-22 (IL-22), also known as IL-10-related T-cell derived inducible factor (IL-TIF), is a member of the IL-10 cytokine family. Mainly produced by activated T-cells and natural killer cells, IL-22 binds to a receptor complex with two components, CRF2-4 and IL-22R. The signaling cascade is said to up-regulate pro-inflammatory cytokines and antimicrobial peptides, and induce production of acutephase reactants in liver and hepatoma cells. The biological function of IL-22 is associated with many inflammatory disorders, including Crohn’s disease, inflammatory bowel disease, psoriasis, rheumatoid arthritis and ulcerative colitis. Thus, IL-22 remains an attractive therapeutic target because of its pro-inflammatory properties.
      References
      Product Information
      Components
      • Assay Buffer
      • Mouse IL-22 Coating Antibody
      • Assay Plate
      • 10X PBS
      • Blocking Buffer
      • Standard Diluent
      • Mouse IL-22 Detection Antibody
      • Mouse IL-22 Standard
      • SMC™ Mouse IL-22 Immunoassay Kit Instructions
      • 10X Wash Buffer
      • Buffer C
      • Elution Buffer B
      Applications
      ApplicationThe sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Mouse IL-22 Discovery Immunoassay unparalleled performance in the quantification of IL-22 in mouse serum.
      Key Applications
      • Single Molecule Counting
      Biological Information
      Species Reactivity
      • Mouse
      Analytes Available
      • IL-22
      Accuracy
      • Minimum of 10 samples spiked with acceptable recovery between 80-120%.
      Physicochemical Information
      Linearity of DilutionMinimum of 10 samples spiked and diluted (at least 3 dilutions) with acceptable recovery between 80-120%.
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size96-well strip plate
      Transport Information
      Supplemental Information
      Specifications