475956 | c-Myc Inhibitor - CAS 403811-55-2 - Calbiochem

475956
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₁₂H₁₁NOS₂403811-55-2

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      475956-10MG
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          Plastic ampoule 10 mg
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          Description
          OverviewA cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (64 μM using c-Myc transfected Rat1a fibroblasts).
          Catalogue Number475956
          Brand Family Calbiochem®
          Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
          References
          ReferencesYin, X., et al. 2003. Oncogene 22, 6151.
          Product Information
          CAS number403811-55-2
          ATP CompetitiveN
          DeclarationSold under license of U.S. Patent 7,026,343.
          FormYellow solid
          Hill FormulaC₁₂H₁₁NOS₂
          Chemical formulaC₁₂H₁₁NOS₂
          ReversibleN
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary Targetc-Myc
          Purity≥95% by HPLC (sum of two isomers)
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Carcinogenic / Teratogenic
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          475956

          References

          Reference overview
          Yin, X., et al. 2003. Oncogene 22, 6151.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-April-2011 RFH
          Synonyms10058-F4, (Z,E)-5-(4-Ethylbenzylidine)-2-thioxothiazolidin-4-one
          DescriptionA cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner both in vitro and in vivo (Effective concentration: 64 µM using c-Myc-transfected Rat1a fibroblasts).
          FormYellow solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number403811-55-2
          Chemical formulaC₁₂H₁₁NOS₂
          Structure formulaStructure formula
          Purity≥95% by HPLC (sum of two isomers)
          SolubilityDMSO (200 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Carcinogenic / Teratogenic
          ReferencesYin, X., et al. 2003. Oncogene 22, 6151.