495455 | Oligomycin - CAS 1404-19-9 - Calbiochem

495455
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      Overview

      Replacement Information

      Key Spec Table

      Empirical FormulaCAS #
      C₄₅H₇₄O₁₁1404-19-9

      Pricing & Availability

      Catalogue NumberAvailability Packaging Qty/Pack Price Quantity
      495455-10MG
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      In Stock 
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          Plastic ampoule 10 mg
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          Description
          OverviewA mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
          Catalogue Number495455
          Brand Family Calbiochem®
          References
          ReferencesWolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
          Product Information
          CAS number1404-19-9
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₄₅H₇₄O₁₁
          Chemical formulaC₄₅H₇₄O₁₁
          ReversibleN
          Structure formula Image
          Applications
          ApplicationOligomycin, CAS 1404-19-9, is a macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase and prevents phosphoryl group transfer. It is a mixture of A, B, and C isomers.
          Biological Information
          Primary TargetMembrane-bound mitochondrial ATPase (F1)
          Purity≥90% by HPLC (mixture of A, B, and C isomers)
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSRK3325000
          Safety Information
          R PhraseR: 36/38

          Irritating to eyes and skin.
          S PhraseS: 26

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          SDS

          Title

          Safety Data Sheet (SDS) 

          Certificates of Analysis

          TitleLot Number
          495455

          References

          Reference overview
          Wolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision11-July-2012 JSW
          DescriptionA mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
          FormWhite solid
          CAS number1404-19-9
          RTECSRK3325000
          Chemical formulaC₄₅H₇₄O₁₁
          Structure formula
          Purity≥90% by HPLC (mixture of A, B, and C isomers)
          SolubilityEthanol (250 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
          Toxicity Irritant
          Merck USA index14, 6833
          ReferencesWolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.