Mycoplasma Testing

 
 

Why Test for Mycoplasmas in
Biopharmaceutical Manufacturing?

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Mycoplasma contamination is a widespread and reoccurring problem in a wide variety of cell culture systems. These micro-organisms, which belong to the class Mollicutes, are comparatively small (0.2 – 0.3 µm), lack a cell wall and are thus not susceptible to penicillins or other antibiotics that act on this structure, and they show tolerance to many other antibiotics. This allows them to grow to high titers in culture media without exhibiting typical bacterial contamination signs, like turbidity.

Contamination of a bioreactor can lead to significant loss of time, materials and revenue unless identified early in the process. In fact, microbial contamination is one of the primary reasons for batch failure in biopharmaceutical production. It is therefore important to test for mycoplasmas at various points in the manufacturing process. To this end, Merck provides both compendial and rapid solutions for reliable Mycoplasma detection.

Mycoplasma Testing
 
 
Mycoplasma Culture Media Brochure

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Mycoplasma Culture Media

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Pharmaceutical User Testimonial

Pharmaceutical User Testimonial

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Events

Mar 17
17/03/19 - 21/03/19
Pittcon 2019
Pennsylvania Convention Center
Philadelphia, Pa, USA
North America 20190317
Mar 20
20/03/19 - 22/03/19
Labortraining: Praxis der Mikrobiologie und Identifizierung
Beuth Hochschule für Technik
Berlin, Germany
Water Purification,Reagents Chemicals and Labware,Industrial Biomonitoring,Analytics and Sample Preparation Europe 20190320
Mar 26
26/03/19 - 28/03/19
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