Optimization for Virus Safety


Step 3

Producing protein at the lowest cost per gram requires that you design and implement a consistent, well-defined virus strategy and optimization process. Achieving these goals also saves you time and materials and maximizes product recovery.

Optimizing a virus filtration process involves evaluating the effect of a variety of process parameters to arrive at conditions that will ensure a robust, consistent, economical, and scalable operation.

For more than 20 years, Merck has been working side-by-side with industry-leading researchers and manufacturers helping them achieve the lowest possible cost for unit operations by successfully tackling some of the same challenges you are facing, such as:
  • How do I prevent costly product dilutions?
  • How do avoid costly buffer changes?
  • What process steps can I combine or streamline without compromising product purity?
  • What filtration methods will deliver the best results without locking me into a specific process?

Merck can help you achieve your goals at every step of the virus clearance operation by working with you to:

  • Minimize your processing time
  • Maximize product recovery
  • Maximize your LRV

Are you leveraging the full resources of Merck?
Contact the Viresolve® Team to learn more about how we can help.


 
 
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Parvovirus Retentive Filter Spiking Study Best Practices

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