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676473 VEGF₁₂₁, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Vascular Endothelial Growth Factor₁₂₁

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676473
  
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      Overview

      Replacement Information

      Key Spec Table

      Purity
      ≥90% by SDS-PAGE
      Description
      Overview

      This product has been discontinued.



      Recombinant, human VEGF121 (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF121 is dominantly expressed in most tumor cell lines. Forms a biologically active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.
      Catalogue Number676473
      Brand Family Calbiochem®
      SynonymsVascular Endothelial Growth Factor₁₂₁
      References
      ReferencesStimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
      Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
      Wilting, J., et al. 1996. Dev. Biol. 176, 76.
      Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.
      Product Information
      FormLyophilized
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
      Purity≥90% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -70°C. Stock solutions are stable for up to 3 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      676473 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      VEGF₁₂₁, Human, Recombinant, S. frugiperda SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Stimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
      Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
      Wilting, J., et al. 1996. Dev. Biol. 176, 76.
      Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-February-2019 JSW
      SynonymsVascular Endothelial Growth Factor₁₂₁
      DescriptionRecombinant, human VEGF121 (121-amino acid splice variant of the human vascular endothelial growth factor VEGF) expressed in S. frugiperda insect cells. VEGF121 is dominantly expressed in most tumor cell lines. Forms a biological active homodimer and evidence suggests that it is also biologically active as a heterodimer with other VEGF splice variants or PIGF.
      FormLyophilized
      Purity≥90% by SDS-PAGE
      Biological activityED₅₀ ≥1 ng/ml as measured by the stimulation of ³H-thymidine incorporation by human umbilical vein endothelial cells and bovine aortic endothelial cells. In vivo effects using the 13-day-old chick chorioallantoic membrane (CAM) assay can be seen between 0.5-4 µg
      Solubility0.1 M acetic acid or H₂O.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -70°C. Stock solutions are stable for up to 3 months at -70°C.
      Toxicity Standard Handling
      ReferencesStimpfl, M., et al. 2002. Clin. Cancer Res. 8, 2253.
      Pufe, T., et al. 2001. Arthritis Rheum. 44, 1082.
      Wilting, J., et al. 1996. Dev. Biol. 176, 76.
      Conn, G. et al. 1990. Proc. Natl. Acad. Sci. USA 87, 1323.