AB9756 Anti-Ghrelin Antibody, active

AB9756
100 µg  
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      概要

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      主要スペック表

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M ELISA Ch Affinity Purified Polyclonal Antibody
      Description
      Catalogue NumberAB9756
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Ghrelin Antibody, active
      References
      Product Information
      FormatAffinity Purified
      PresentationLiquid in PBS with 0.02% sodium azide.
      Applications
      ApplicationDetect the Ghrelin protein using this Anti-Ghrelin, active validated for use in ELISA.
      Key Applications
      • ELISA
      Application NotesELISA: 1:500-1:4,000 in a sandwich ELISA.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPeptide from ghrelin, active.
      HostChicken
      SpecificityGhrelin, active
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryGhrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM]
      Gene Symbol
      • GHRL
      • ghrelin
      • obestatin
      • MTLRP
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
      SIZE: 117 amino acids; 12911 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
      PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
      SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Ghrelin Antibody, active (M)SDS

      タイトル

      英語版製品安全データシート((M)SDS) 

      Anti-Ghrelin Antibody, active 試験成績書(CoA)

      タイトルロット番号
      CHICKEN ANTI- GHRELIN, ACTIVE2470382
      CHICKEN ANTI- GHRELIN, ACTIVE - 24939182493918
      CHICKEN ANTI- GHRELIN, ACTIVE -25101282510128
      CHICKEN ANTI- GHRELIN, ACTIVE -25729742572974
      CHICKEN ANTI- GHRELIN, ACTIVE -25868282586828
      CHICKEN ANTI- GHRELIN, ACTIVE -25955522595552
      CHICKEN ANTI- GHRELIN, ACTIVE -26081672608167
      CHICKEN ANTI- GHRELIN, ACTIVE -26220352622035
      CHICKEN ANTI- GHRELIN, ACTIVE -26411192641119
      CHICKEN ANTI- GHRELIN, ACTIVE -26574732657473

      データシート

      タイトル
      CHICKEN ANTI- GHRELIN, ACTIVE

      FAQ(よくある質問と回答)

      質問回答
      What is the difference between active and total Ghrelin RIAs/ELISAs?The active assays require the intact octanoyl group on the 3rd AA which means samples need to be acidified and treated with aprotinin, while total/desacyl assays can read the truncated form without the octanoyl modification.

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      カテゴリー

      Life Science Research > Antibodies and Assays > Primary Antibodies