Fmoc-PAL-AM resin consists of Barany's aminomethyl-dimethoxyphenoxyvaleric acid linker  attached to aminomethylated polystyrene. The amino group of this linker can be easily acylated under standard coupling conditions. Following peptide assembly, treatment with 95% TFA containing scavengers releases the desired peptide amide. Studies have shown the acid sensitivity of this linker to be around twice that of the Rink amide linker . There is some evidence to suggest that PAL resins give greater yields in microwave assisted synthesis.
3903 90 90
Structure formula Image
Safety Information according to GHS
10 - 13 Other liquids and solids
WGK 1 slightly water endangering
3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Product Usage Statements
Storage and Shipping Information
Store at +2°C to +8°C.
white to yellow to beige
Appearance of substance (visual)
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF)