HCVD5MAG-67K MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 5 - Cardiovascular Disease (CVD) Multiplex Assay

HCVD5MAG-67K
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概要

Replacement Information

主要スペック表

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
ADAM15, MR-ProADM, sCD163, CDH13, CHGA, HSP60, IGF-1R, LDLR, LEPR, Notch1, PLA2G7, PTGDS, sST2, SYND4 H Mplex Luminex xMAP
Description
Catalogue NumberHCVD5MAG-67K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 5 - Cardiovascular Disease (CVD) Multiplex Assay
OverviewThe MILLIPLEX® MAP Human Cardiovascular Disease Magnetic Bead Panel 5 may be used to simultaneously quantify any or all the the following: Disintegrin and metalloproteinase domain-containing protein 15
(ADAM15), Mid region of proADM protein (MR-ProADM), Soluble savenger receptor cysteine-rich
type 1 protein M130 (sCD163), Cadherin-13 (CDH13), Chromogranin-A (CHGA), Heat shock
protein 60 (HSP60), Insulin-like growth factor 1 receptor (IGF1R), Low-density lipoprotein
receptor (LDLR), Leptin receptor (LEPR), Neurogenic locus notch homolog protein 1 (Notch1),
Platelet-activating factor acetylhydrolase (PLA2G7), Prostaglandin-H2 D-isomerase (PTGDS),
Soluble interleukin-1 receptor-like 1 (sST2), Syndecan 4 (SYND4).
Background InformationCardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Inter-assay: < 15%
  • Intra-Assay: < 10%
Panel TypeMAGNETIC Cardiovascular
Applications
ApplicationThe analytes available for this multiplex kit are: ADAM15, MR-ProADM, sCD163, CDH13, CHGA, HSP60, IGF1R, LDLR, LEPR, Notch1, PLA2G7, PTGDS, sST2 and SYND4.
Key Applications
  • Multiplexing
Application Notes
For optimal sensitivity, use an overnight (16-18 hour) incubation. A two hour incubation can also be used (though sensitivity may be lower). Serum and plasma samples require (recommend) a 1:5 dilution with Assay Buffer. Tissue culture supernatants may be run neat or or appropriately diluted in control medium. Each well requires 25 μL of sample, standard or control.
Biological Information
SpecificityCross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Species Reactivity
  • Human
Analytes Available
  • ADAM15
  • MR-ProADM
  • sCD163
  • CDH13
  • CHGA
  • HSP60
  • IGF-1R
  • LDLR
  • LEPR
  • Notch1
  • PLA2G7
  • PTGDS
  • sST2
  • SYND4
Assay PanelEverything you need in a single kit.
Cross ReactivityThere was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Accuracy
  • ADAM15 82%
  • MR-ProADM 97%
  • sCD163 88%
  • CDH13 82%
  • CHGA 86%
  • HSP60 71%
  • IGF1R 89%
  • LDLR 88%
  • LEPR 89%
  • Notch1 91%
  • PLA2G7 88%
  • PTGDS 87%
  • sST2 89%
  • SYND4 91%
Physicochemical Information
Sensitivity
  • See kit protocol for individual analytes sensitivities.
Linearity of DilutionContact technical support for this information
Standard Curve Range
  • ADAM15: 49-200,000 pg/mL
  • MR-ProADM: 4.9-20,000 pg/mL
  • sCD163: 0.24-1,000 ng/mL
  • CDH13: 49-200,000 pg/mL
  • CHGA: 49-200,000 pg/mL
  • HSP60: 0.49-2,000 ng/mL
  • IGF1R: 0.49-2,000 ng/mL
  • LDLR: 1.95-8,000 ng/mL
  • LEPR: 195-800,000 pg/mL
  • Notch1: 9.8-40,000 pg/mL
  • PLA2G7: 195-800,000 pg/mL
  • PTGDS: 24-100,000 pg/mL
  • sST2: 98-400,000 pg/mL
  • SYND4: 4.9-20,000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Transport Information
Supplemental Information
Specifications

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カテゴリー

Life Science Research > Protein Detection and Quantification > Immunoassays > Multiplexed Immunoassays > Milliplex MAP Assay Products > Configurable Kits
Life Science Research > Antibodies and Assays > Immunoassays > Multiplexed Immunoassays > Milliplex MAP Assay Products > Configurable Kits