495455 | Oligomycin - CAS 1404-19-9 - Calbiochem

495455
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      Overview

      주요 사양표

      Empirical FormulaCAS #
      C₄₅H₇₄O₁₁1404-19-9

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      495455-10MGCN
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          10 mg
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          Description
          Overview A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
          Catalogue Number 495455
          Brand Family Calbiochem®
          References
          References Wolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
          Product Information
          CAS number 1404-19-9
          ATP Competitive N
          Form White solid
          Hill Formula C₄₅H₇₄O₁₁
          Chemical formula C₄₅H₇₄O₁₁
          Molar Mass 791.1
          Reversible N
          Structure formula Image
          Applications
          Biological Information
          Primary Target Membrane-bound mitochondrial ATPase (F1)
          Purity ≥90% by HPLC (mixture of A, B, and C isomers)
          Physicochemical Information
          Cell permeable N
          Solubility EtOH
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECS RK3325000
          Safety Information
          R Phrase R: 36/38

          Irritating to eyes and skin.
          S Phrase S: 26

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Do not freeze No
          Special Instructions Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          MSDS

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          Certificates of Analysis

          TitleLot Number
          495455

          References

          참고문헌 보기
          Wolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision 11-July-2012 JSW
          Description A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
          Form White solid
          CAS number 1404-19-9
          RTECS RK3325000
          Molar mass 791.1
          Chemical formula C₄₅H₇₄O₁₁
          Structure formula
          Purity ≥90% by HPLC (mixture of A, B, and C isomers)
          Solubility Ethanol (250 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze No
          Special Instructions Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
          Toxicity Irritant
          Merck USA index 14, 6833
          References Wolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
          Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
          Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
          Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.