SupraSolv®


Solvents for Headspace GC Analysis of Residual Solvents According to Ph Eur and USP

SupraSolv® headspace is Merck’s range of solvents specially designed for headspace gas chromatography. Headspace GC is the preferred method for the analysis of residual solvents in actives, excipients, and drug products according to Ph Eur and USP.

Accurate analysis with headspace gas chromatography requires the use of very pure solvents with extremely low concentrations of the defined residual solvents. We ensure this high purity through special, state-of-the-art production processes, and we specify for our high-purity SupraSolv® headspace solvents the concentrations of all the residual solvents classified in the relevant ICH guideline Q3C “Impurities: Guideline for Residual Solvents”.

Moreover, we perform application tests on every single batch of SupraSolv® headspace – thus we are able to consistently deliver you the reliability, accuracy and analytical safety you need.

Catalog Number Catalog Name
102497 1-Methyl-2-pyrrolidone
102695 Benzyl alcohol
100399 N,N-Dimethylacetamide
100577 Water
100202 N,N-Dimethylformamide
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