05-23-0701 Neurokinin A - CAS 86933-74-6 - Calbiochem

05-23-0701
  
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      Tableau de caractéristiques principal

      Empirical FormulaCAS #
      C₅₀H₈₀N₁₄O₁₄S 86933-74-6
      Description
      OverviewPeptide belonging to the tachykinin family. A more potent bronchioconstrictor than substance P. May be released in association with the activation of polymodal C-nociceptors. May regulate neutrophil recruitment into lower respiratory tract. Exhibits higher affinity for NK-2 receptors compared to NK-1 or NK-3 and plays a role in hematopoietic regulation.
      Catalogue Number05-23-0701
      Brand Family Calbiochem®
      SynonymsNKA, Substance K, HKTDSFVGLM-NH₂, Neuromedin L
      References
      ReferencesRameshwar, P., and Gascom, P. 1996. Blood 88, 98.
      Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
      Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
      von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
      Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.
      Product Information
      CAS number86933-74-6
      FormWhite to off-white solid
      FormulationSupplied as an trifluoroacetate salt.
      Hill FormulaC₅₀H₈₀N₁₄O₁₄S
      Chemical formulaC₅₀H₈₀N₁₄O₁₄S
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Certificats d'analyse

      TitreNuméro de lot
      05-23-0701

      Références bibliographiques

      Aperçu de la référence bibliographique
      Rameshwar, P., and Gascom, P. 1996. Blood 88, 98.
      Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
      Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
      von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
      Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.
      Fiche technique

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsNKA, Substance K, HKTDSFVGLM-NH₂, Neuromedin L
      DescriptionPeptide belonging to the tachykinin family. A more potent bronchio-constrictor than substance P. May be released in association with the activation of polymodal c-nociceptors. May regulate neutrophil recruitment into lower respiratory tract. Exhibits higher affinity for NK-2 receptors compared to NK-1 or NK-3 and plays a role in hematopoietic regulation.
      FormWhite to off-white solid
      FormulationSupplied as an trifluoroacetate salt.
      CAS number86933-74-6
      Chemical formulaC₅₀H₈₀N₁₄O₁₄S
      Peptide SequenceH-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH₂
      Purity≥95% by HPLC
      Solubility5% Acetic Acid (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesRameshwar, P., and Gascom, P. 1996. Blood 88, 98.
      Chan, C.C., et al. 1993. Can. J. Physiol. Pharmacol. 72, 11.
      Nagahisa, A., et al. 1992. Eur. J. Pharmacol. 217, 191.
      von Essen, S.G., et al. 1992. Am. J. Physiol. 263, L226.
      Xu, X.J., and Wiesenfeld-Hallin, A. 1992. Acta Physiol. Scand. 144, 63.

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      Catégories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Neurochemicals > Neuropeptides