116814 Adenosine 3ʹ,5ʹ-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt - CAS 151837-09-1 - Calbiochem

116814
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH 151837-09-1

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1116814-5UMOL
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          Frasco de vidrio 5 umol
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          Description
          OverviewA cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 µM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.
          Note: 5 µmol = 2.23 mg.
          Catalogue Number116814
          Brand Family Calbiochem®
          SynonymsAdenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V
          References
          ReferencesKaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
          Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
          Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
          Butt, E., et al. 1990. FEBS Lett. 263, 47.
          Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
          Rothermel, J.D. 1988. Biochem. J. 251, 757.
          Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
          de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
          O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.
          Product Information
          CAS number151837-09-1
          ATP CompetitiveN
          FormCrystalline solid
          Hill FormulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
          Chemical formulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetPKA
          Primary Target K<sub>i</sub>11 µM against protein kinase A
          Purity≥98% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          116814

          Referencias bibliográficas

          Visión general referencias
          Kaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
          Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
          Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
          Butt, E., et al. 1990. FEBS Lett. 263, 47.
          Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
          Rothermel, J.D. 1988. Biochem. J. 251, 757.
          Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
          de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
          O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.

          Folleto

          Cargo
          Inhibitor Sourcebook 3rd Edition - Merck
          Nucleotides and Bases Technical Bulletin
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision06-September-2007 RFH
          SynonymsAdenosine 3ʹ,5ʹ-cyclic Phosphorothioate-Rp, Rp-cAMPS, TEA, PKA Inhibitor V
          DescriptionCell permeable inhibitor of protein kinase A (Ki = 11 µM). Resistant to hydrolysis by phosphodiesterases. Note: 5 µmol = 2.23 mg
          FormCrystalline solid
          CAS number151837-09-1
          Chemical formulaC₁₀H₁₁N₅O₅PS · (CH₃CH₂)₃NH
          Structure formulaStructure formula
          Purity≥98% by HPLC
          SolubilityH₂O (20 mg/ml)
          Storage -20°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
          Toxicity Standard Handling
          ReferencesKaji, H., et al. 1992. Biochem. Biophys. Res. Commun. 182, 1356.
          Van der Kloot, W., and Branisteanu, D.D. 1992. Eur. J. Phys. 420, 336.
          Yokozaki, H., et al. 1992. Cancer Res. 52, 2504.
          Butt, E., et al. 1990. FEBS Lett. 263, 47.
          Dostmann, W.R., et al. 1990. J. Biol. Chem. 265, 10484.
          Rothermel, J.D. 1988. Biochem. J. 251, 757.
          Eckstein, F. 1985. Annu. Rev. Biochem. 54, 367.
          de Wit, R.J., et al. 1984. Eur. J. Biochem. 142, 255.
          O'Brian, C.A., et al. 1982. Biochemistry 21, 4371.