05-23-2540 | Amylin, Human - CAS 122384-88-7 - Calbiochem

05-23-2540
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₁₆₅H₂₆₁N₅₁O₅₅S₂ 122384-88-7

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US105232540-0.5MG
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      Disponibilidad a confirmarDisponibilidad a confirmar
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      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
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          Ampolla de plást. 0.5 mg
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          Description
          OverviewA 37-amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anorectic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin.
          Catalogue Number05-23-2540
          Brand Family Calbiochem®
          SynonymsIslet Amyloid Polypeptide
          References
          ReferencesBaque, S., et al. 1994. Biochem. J. 304, 449.
          Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
          Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
          Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.
          Product Information
          CAS number122384-88-7
          ATP CompetitiveN
          DeclarationNot for sale in the United States.
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
          Chemical formulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
          ReversibleN
          Sold on the basis of peptide contentY
          Applications
          Biological Information
          Primary TargetHas anorectic effects in rats
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Peptide ContentY
          Peptide SequenceH-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          05-23-2540

          Referencias bibliográficas

          Visión general referencias
          Baque, S., et al. 1994. Biochem. J. 304, 449.
          Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
          Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
          Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-June-2017 JSW
          SynonymsIslet Amyloid Polypeptide
          DescriptionA 37 amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anoretic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin.
          FormWhite to off-white lyophilized solid
          FormulationSupplied as a trifluoroacetate salt.
          CAS number122384-88-7
          Chemical formulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
          Peptide SequenceH-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
          Purity≥95% by HPLC
          Solubility5% acetic acid (1 mg/ml)
          Storage -20°C
          Protect from moisture
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesBaque, S., et al. 1994. Biochem. J. 304, 449.
          Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
          Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
          Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.