176904 Anthrax Lethal Factor Protease Substrate III, Fluorogenic - Calbiochem

176904
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical Formula
      C₉₁H₁₅₆N₄₂O₁₈

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1176904-1MG
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          Ampolla de plást. 1 mg
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          Description
          OverviewAn N-acetylated, C-7-amido-4-methylcoumarin (AMC) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax lethal factor (LF) metalloproteolytic activity with a detection limit of ~5-10 pM. Reported to be useful for high-throughput screening of LF inhibitors.
          Catalogue Number176904
          Brand Family Calbiochem®
          SynonymsAnthrax LF Protease Substrate III, Fluorogenic, Bacillus anthracis LF Protease Substrate III, Fluorogenic
          References
          ReferencesTonello, F., et. al. 2002. Nature 418, 386.
          Product Information
          ATP CompetitiveN
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Hill FormulaC₉₁H₁₅₆N₄₂O₁₈
          Chemical formulaC₉₁H₁₅₆N₄₂O₁₈
          Hygroscopic Hygroscopic
          ReversibleN
          Applications
          Biological Information
          Primary TargetMeasuring Anthrax lethal factor (LF) metalloproteolytic activity
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableN
          Emission max.
          Excitation max.
          Peptide SequenceAc-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-AMC
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          176904

          Referencias bibliográficas

          Visión general referencias
          Tonello, F., et. al. 2002. Nature 418, 386.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision15-April-2008 RFH
          SynonymsAnthrax LF Protease Substrate III, Fluorogenic, Bacillus anthracis LF Protease Substrate III, Fluorogenic
          DescriptionAn N-acetylated, C-7-amido-4-methylcoumarin (AMC) derivative of a 14-mer peptide substrate designed from the MEK-2 template that is useful for measuring Anthrax Lethal Factor (LF) metalloproteolytic activity with a detection limit of ~5-10 pM. Reported to be useful for high-throughput screening of LF inhibitors. Excitation max.: ~360 nm; emission max.: ~460 nm.
          FormLyophilized
          FormulationSupplied as a trifluoroacetate salt.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₉₁H₁₅₆N₄₂O₁₈
          Peptide SequenceAc-Gly-Tyr-βAla-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Val-Leu-Arg-AMC
          Purity≥97% by HPLC
          SolubilityDMSO (5 mg/ml), 5% Acetic Acid (5 mg/ml), or H₂O (1 mg/ml)
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesTonello, F., et. al. 2002. Nature 418, 386.