181198 Arachidonic Acid - CAS 506-32-1 - Calbiochem

181198
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₂₀H₃₂O₂ 506-32-1

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1181198-100MG
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          Frasco de vidrio 100 mg
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          US1181198-1GM
          Comprobando disponibilidad...
          Disponibilidad a confirmarDisponibilidad a confirmar
          En existencia 
          Suspendido
          Cantidades limitadas disponibles
          Debe confirmarse disponibilidad
            El resto: se avisará
              El resto: se avisará
              Se avisará
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              Ampolla de plást. 1 gm
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              Description
              OverviewPrecursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway.
              Catalogue Number181198
              Brand Family Calbiochem®
              Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
              References
              ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
              Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
              Han, J.-W., et al. 1991. Science 252, 576.
              Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
              Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.
              Product Information
              CAS number506-32-1
              ATP CompetitiveN
              FormColorless oil
              Hill FormulaC₂₀H₃₂O₂
              Chemical formulaC₂₀H₃₂O₂
              ReversibleN
              Structure formula ImageStructure formula Image
              Applications
              Biological Information
              Primary TargetRas-GAP
              Purity≥99% by TLC and GC
              Physicochemical Information
              Cell permeableN
              Dimensions
              Materials Information
              Toxicological Information
              Safety Information according to GHS
              RTECSCE6675000
              Safety Information
              R PhraseR: 20/21/22-36/37/38

              Harmful by inhalation, in contact with skin and if swallowed.
              Irritating to eyes, respiratory system and skin.
              S PhraseS: 36-26

              Wear suitable protective clothing.
              In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
              Product Usage Statements
              Storage and Shipping Information
              Ship Code Dry Ice Only
              Toxicity Harmful
              Storage ≤ -70°C
              Protect from Light Protect from light
              Do not freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Packaging Information
              Packaged under inert gas Packaged under inert gas
              Transport Information
              Supplemental Information
              Specifications

              Documentation

              Ficha datos de seguridad (MSDS)

              Título

              Ficha técnica de seguridad del material (MSDS) 

              Certificados de análisis

              CargoNúmero de lote
              181198

              Referencias bibliográficas

              Visión general referencias
              Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
              Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
              Han, J.-W., et al. 1991. Science 252, 576.
              Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
              Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.

              Folleto

              Cargo
              Nitric Oxide and Oxidative Stress Brochure
              Ficha técnica

              Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

              Revision15-April-2008 RFH
              Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, 20:4
              DescriptionA cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets.
              FormColorless oil
              Intert gas (Yes/No) Packaged under inert gas
              CAS number506-32-1
              RTECSCE6675000
              Chemical formulaC₂₀H₃₂O₂
              Structure formulaStructure formula
              Purity≥99% by TLC and GC
              SolubilityEthanol (5 mg/ml)
              Storage ≤ -70°C
              Protect from light
              Do Not Freeze Ok to freeze
              Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
              Toxicity Harmful
              Merck USA index14, 765
              ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
              Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
              Han, J.-W., et al. 1991. Science 252, 576.
              Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
              Neddleman P., et al. 1986. Annu. Rev. Biochem. 55, 69.