124015 InSolution™ Akt Inhibitor IV - Calbiochem

124015
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical Formula
      C₃₁H₂₇IN₄S

      Precios y disponibilidad

      Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
      US1124015-1MG
      Comprobando disponibilidad...
      Disponibilidad a confirmarDisponibilidad a confirmar
      En existencia 
      Suspendido
      Cantidades limitadas disponibles
      Debe confirmarse disponibilidad
        El resto: se avisará
          El resto: se avisará
          Se avisará
          Póngase en contacto con el Servicio de Atención al Cliente
          Contact Customer Service

          Ampolla de plást. 1 mg
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          Description
          Catalogue Number124015
          Brand Family Calbiochem®
          References
          ReferencesKau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.


          Product Information
          ATP CompetitiveN
          FormLiquid
          FormulationA 10 mM (1 mg/163 µl) solution of Akt Inhibitor IV (Cat. No. 124011) in DMSO.
          Hill FormulaC₃₁H₂₇IN₄S
          Chemical formulaC₃₁H₂₇IN₄S
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Primary TargetAkt
          Primary Target IC<sub>50</sub>625 nM and <1.25 µM in blocking Akt-mediated FOXO1a nuclear export and cell proliferation, respectively, in 786-O cells
          Purity≥98% by HPLC
          Concentration Label Please refer to vial label for lot-specific concentration
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Irritant
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Licencias necesarias

          Título
          CARTA DE USO GENERAL 2016
          PRODUCTO REGULADO POR LA SAGARPA
          PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

          InSolution™ Akt Inhibitor IV - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          InSolution™ Akt Inhibitor IV - Calbiochem Certificados de análisis

          CargoNúmero de lote
          124015

          Referencias bibliográficas

          Visión general referencias
          Kau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.


          Folleto

          Cargo
          Akt
          Biologics 31.1
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision09-April-2008 RFH
          DescriptionA cell-permeable benzimidazole compound that inhibits Akt phosphorylation/activation presumably by targeting the ATP binding site of a kinase upstream of Akt, but downstream of PI3K. Shown to block Akt-mediated FOXO1a nuclear export (IC50 = 625 nM) and cell proliferation (IC50 < 1.25 µM) in 786-O cells. Unlike phosphatidylinositol analog-based Akt inhibitors (Cat. Nos. 124005, 124008, 124009), this inhibitor does not affect PI3K.
          FormLiquid
          FormulationA 10 mM (1 mg/163 µl) solution of Akt Inhibitor IV (Cat. No. 124011) in DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          Concentration Label Please refer to vial label for lot-specific concentration
          Chemical formulaC₃₁H₂₇IN₄S
          Structure formulaStructure formula
          Purity≥98% by HPLC
          Storage +2°C to +8°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial use, aliquot and refrigerate (4°C).
          Toxicity Irritant
          ReferencesKau, T.R., et al. 2003. Cancer Cell 4, 463.



          Selected Citations
          Lee, J., et al. 2009. Cell Stem Cell 5, 76.