106425 | N-Acetyl-L-cysteine - CAS 616-91-1 - Calbiochem

106425
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      Descripción

      Replacement Information

      Tabla espec. clave

      Empirical FormulaCAS #
      C₅H₉NO₃S 616-91-1

      Precios y disponibilidad

      Número de referenciaDisponiblidad Embalaje Cant./Env. Precio Cantidad
      US1106425-5GM
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      Disponibilidad a confirmarDisponibilidad a confirmar
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          Ampolla de plást. 5 gm
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          Description
          OverviewMucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
          Catalogue Number106425
          Brand Family Calbiochem®
          SynonymsLNAC
          References
          ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
          Product Information
          CAS number616-91-1
          FormWhite solid
          Hill FormulaC₅H₉NO₃S
          Chemical formulaC₅H₉NO₃S
          Structure formula ImageStructure formula Image
          Applications
          Biological Information
          Purity≥98% by titration
          Physicochemical Information
          ContaminantsFe: ≤20 ppm
          Cl: ≤ 0.04%
          Sulfate: ≤ 0.03%
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSHA1660000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +15°C to +30°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Certificados de análisis

          CargoNúmero de lote
          106425

          Referencias bibliográficas

          Visión general referencias
          Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.

          Folleto

          Cargo
          Caspases and other Apoptosis Related Tools Brochure
          Nitric Oxide and Oxidative Stress Brochure

          Citas

          Título
        • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.
        • Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision01-May-2017 JSW
          SynonymsLNAC
          DescriptionA mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number616-91-1
          RTECSHA1660000
          Chemical formulaC₅H₉NO₃S
          Structure formulaStructure formula
          Purity≥98% by titration
          ContaminantsFe: ≤20 ppm
          Cl: ≤ 0.04%
          Sulfate: ≤ 0.03%
          SolubilityH₂O (50 mg/ml)
          Storage +15°C to +30°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 88
          ReferencesOrtolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
          Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
          Ferrari, G., et al. 1995. J. Neurosci. 15, 2857.
          Weinander, R., et al. 1994. J. Biol. Chem. 269, 71.
          Citation
        • Teresa Sanchez Alcaraz, et al. (2004) Involvement of Glutathione as a Mechanism of Indirect Protection against Spontaneous Ex Vivo Apoptosis Associated with Bovine Leukemia Virus. Journal of Virology 78, 6180-6190.