ABE1374 | Anti-EGR-2 Antibody

ABE1374
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE1374
      DescriptionAnti-EGR-2 Antibody
      Alternate Names
      • E3 SUMO-protein ligase EGR2
      • AT591
      • Early growth response protein 2
      • EGR-2
      • Zinc finger protein Krox-20
      Background InformationEGR-2 is a DNA binding transcription factor the helps control the expression of many genes important in brain development, brain segmentation, and facial nerve structural organization as well as other proteins important in the gonadotropin response, fat cell differentiation, apoptosis, ossification and many other systems. EGR-2 is one of handful of transcriptions factors that is regulated via protein sumoylation as well. Mutations in EGR-2 are linked to a number of syndromes affecting the nervous system including Congenital hypomyelinating Neuropathy, Charcot-Marie Tooth disease, and Dejerine Sotlas Syndrome.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.
      Applications
      ApplicationThis Anti-EGR-2 Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of EGR-2.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:100 dilution from a representative lot was reported to detect EGR-2 in HeLa, 293T, Capan-2, SAOS-2, SH-SY5Y, and SKIN 3 cells.
      Biological Information
      ImmunogenSet of three peptides situated near the N-terminal region of EGR-2 isoform1.
      EpitopeN-terminal region between amino acides 1-150
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityRecognizes EGR-2
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EGR2
      • KROX20
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~ 45 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: A 1 µg/mL dilution of this antibody detected EGR-2 in a A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications