06-106 | Anti-IGFBP-1 Antibody

200 µL  
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      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HICC, IP, WBRbSerumPolyclonal Antibody
      Catalogue Number06-106
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionAnti-IGFBP-1 Antibody
      Product Information
      ApplicationDetect IGFBP-1 using this Anti-IGFBP-1 Antibody validated for use in IC, IP & WB.
      Key Applications
      • Immunocytochemistry
      • Immunoprecipitation
      • Western Blotting
      Biological Information
      ImmunogenIGFBP-1 purified from human amniotic fluid
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
      Gene Symbol
      • IGFBP1
      • IBP1
      • AFBP
      • PP12
      • IGF-BP25
      • hIGFBP-1
      • IGFBP-1
      Purification MethodAntiserum
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P08833 # IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
      SIZE: 259 amino acids; 27904 Da
      SUBUNIT: Binds equally well IGF1 and IGF2.
      PTM: Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.
      SIMILARITY: SwissProt: P08833 ## Contains 1 IGFBP N-terminal domain. & Contains 1 thyroglobulin type-1 domain.
      Molecular Weight30kDa
      Physicochemical Information
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by immunoblot on IGFBP-1 (Catalog #12-129)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsLyophilized: 2 years at 4°C Rehydrated: 6 months at -20°C
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information


      Certificates of Analysis

      TitleLot Number
      Anti-IGFBP-1 (rabbit antiserum) - 2360517 2360517
      Anti-IGFBP-1 (rabbit antiserum) - 2290357 2290357
      Anti-IGFBP-1 - 12477 12477
      Anti-IGFBP-1 - 16592 16592
      Anti-IGFBP-1 - 27636 27636
      Anti-IGFBP-1_2834620 2834620


      Reference overviewPub Med ID
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      Himeda, T; Hosomi, T; Okuwa, T; Muraki, Y; Ohara, Y
      PloS one  8  e53194  2013

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      Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli.
      Yuhki, M; Kajitani, T; Mizuno, T; Aoki, Y; Maruyama, T
      Reproductive biology and endocrinology : RB&E  9  104  2011

      Show Abstract Full Text Article
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      C-FLIP promotes the motility of cancer cells by activating FAK and ERK, and increasing MMP-9 expression.
      Deokbum Park,Eunsook Shim,Youngmi Kim,Young Myeong Kim,Hansoo Lee,Jongseon Choe,Dongmin Kang,Yun-Sil Lee,Dooil Jeoung
      Molecules and cells  25  2008

      Show Abstract
      18414015 18414015
      Colocalization of insulin-like growth factor-binding protein with insulin-like growth factor I.
      Kobayashi, S, et al.
      Am. J. Physiol., 261: F22-8 (1991)  1991

      Show Abstract
      1713420 1713420
      Purification of a 31,000-dalton insulin-like growth factor binding protein from human amniotic fluid. Isolation of two forms with different biologic actions.
      Busby, W H, et al.
      J. Biol. Chem., 263: 14203-10 (1988)  1988

      Show Abstract
      2971653 2971653
      Radioimmunoassay of a 26,000-dalton plasma insulin-like growth factor-binding protein: control by nutritional variables.
      Busby, W H, et al.
      J. Clin. Endocrinol. Metab., 67: 1225-30 (1988)  1988

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