MABT493 | Anti-IL-34, clone 1D12 Antibody

MABT493
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IFMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABT493
      DescriptionAnti-IL-34, clone 1D12 Antibody
      Alternate Names
      • Interleukin-34
      • IL-34
      Background InformationIntereukin 34, also known as IL-34 or IL34 is a cytokine that promotes the differentiation and viability of moncytes and macrophages. IL-34 stimulate the phosphorylation of MAPL1/ERK2/ERK2 and MAPK3/ERK1. IL-34 is a ligand for colony-stimulating factor CSF1R. IL-34 is predominantly expressed in spleen, and also detected in a range of other tissues including heart, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
      Applications
      ApplicationAnti-IL-34, clone 1D12 Antibody is an antibody against IL-34 for use in flow cytometry & immunofluorescence.
      Key Applications
      • Flow Cytometry
      • Immunofluorescence
      Application NotesImmunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected IL-34 in U251 cells.
      Biological Information
      ImmunogenPurified recombinant fragment of human IL-34 expressed in E. Coli
      Clone1D12
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • IL34
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight27 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceFlow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected IL-34 in K562 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies