MABN1117 | Anti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody

MABN1117
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbUnpurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN1117
      DescriptionAnti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody
      Alternate Names
      • Pannexin-1
      Background InformationPannexin 1 (PANX1) belongs to the innexin family. Innexin family members are the structural components of gap junctions. Pannexin 1 and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that Pannexin 1 alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
      References
      Product Information
      FormatUnpurified
      PresentationRabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.
      Applications
      ApplicationThis Anti-Pannexin 1, clone EPR5556, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of Pannexin 1.
      Key Applications
      • Western Blotting
      Application NotesProduced in collaboration with Epitomics™
      Biological Information
      ImmunogenSynthetic peptide corresponding to human Pannexin 1.
      CloneEPR5556
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • PANX1
      • MRS1
      • UNQ2529/PRO6028
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~48 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human fetal brain, SH-SY5Y, Caco-2, and NIH:OVACAR-3 lysates.

      Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected Pannexin 1 in human fetal brain, SH-SY5Y, Caco-2, and NIH:OVACAR-3 lysates.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications

      Related Products & Applications

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies